Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 3/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 6/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.34 |
| ▸ | RXRA | P19793 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.34 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 2/20 | 0.33 |
| ▸ | PELI1 | Q96FA3 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20153036 | 0.79 | CNR2 (0.39) | APPGABRA1GABRB2MAPTMEN1 | |
| SCHEMBL19847594 | 0.68 | MAOA (0.40) | APPALOX5MAPTMEN1POLB | |
| SCHEMBL29171599 | 0.67 | APP (0.48) | APPALOX5GABRA1GABRB2MAPT | |
| Cyanide SCHEMBL28038481 | 0.67 | — | — | |
| Methylamine SCHEMBL28044974 | 0.67 | — | — | |
| Boric Acid SCHEMBL29171600 | 0.67 | APP (0.48) | APPALOX5GABRA1GABRB2MAPT | |
| SCHEMBL12667819 | 0.66 | — | — | |
| Formic Acid SCHEMBL27598190 | 0.64 | APP (0.44) | APPALOX5GABRA1GABRB2MAPT | |
| SCHEMBL27963762 | 0.64 | APP (0.44) | APPALOX5GABRA1GABRB2MAPT | |
| SCHEMBL30668980 | 0.64 | MCL1 (0.56) | APPALOX5MAPTCNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210070787-A1 | Mito-Honokiol Compounds and Methods of Synthesis and Use Thereof | AIX-MARSEILLE UNIVERSITE (FR) | 2021-03-11 | — | — | US | disclosed |
| US-10836782-B2 | Mito-honokiol compounds and methods of synthesis and use thereof | THE MEDICAL COLLEGE OF WISCONSIN, INC. (US) | 2020-11-17 | — | — | US | disclosed |
| US-20180134737-A1 | MITO-HONOKIOL COMPOUNDS AND METHODS OF SYNTHESIS AND USE THEREOF | THE MEDICAL COLLEGE OF WISCONSIN, INC. | 2018-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180134737-A1 | MITO-HONOKIOL COMPOUNDS AND METHODS OF SYNTHESIS AND USE THEREOF | MFN2, MT-ND2, PCK2 | APP 3838/4885ALOX5 346/4885GABRA1 4171/4885 |
| US-20210070787-A1 | Mito-Honokiol Compounds and Methods of Synthesis and Use Thereof | CYP11B1, CYP11B2, MFN2 | APP 3026/4885ALOX5 334/4885GABRA1 3416/4885 |
| US-10836782-B2 | Mito-honokiol compounds and methods of synthesis and use thereof | MFN2, MT-ND2, PCK2 | APP 3838/4885ALOX5 346/4885GABRA1 4171/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.