Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OXTR | P30559 | 1/20 | 0.34 |
| ▸ | NNMT | P40261 | 1/20 | 0.33 |
| ▸ | ITGB3 | P05106 | 5/20 | 0.33 |
| ▸ | ITGAV | P06756 | 5/20 | 0.33 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.33 |
| ▸ | ITGA5 | P08648 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.32 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | ITGB6 | P18564 | 2/20 | 0.32 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.32 |
| ▸ | ITGB8 | P26012 | 1/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20153326 | 0.86 | KDM4E (0.40) | OXTRNNMTITGB3ITGAVKMT2A | |
| SCHEMBL21311735 | 0.83 | ITGB3 (0.38) | ITGB3ITGAVITGB1ITGA5ITGB6 | |
| SCHEMBL21311736 | 0.82 | ITGB3 (0.31) | ITGB3ITGAVITGB1ITGA5NR3C1 | |
| SCHEMBL21311737 | 0.81 | OXTR (0.31) | OXTRNR3C1 | |
| SCHEMBL21311584 | 0.77 | ITGB3 (0.38) | ITGB3ITGAVITGB1ITGA5ITGB6 | |
| SCHEMBL7018373 | 0.76 | NNMT (0.42) | OXTRNNMTITGB3ITGAVKMT2A | |
| SCHEMBL13829314 | 0.76 | NNMT (0.42) | OXTRNNMTITGB3ITGAVKMT2A | |
| SCHEMBL20153716 | 0.75 | ALDH1A1 (0.33) | OXTRITGB3ITGAVKMT2AMAPT | |
| SCHEMBL21311583 | 0.75 | ITGAV (0.59) | ITGB3ITGAVITGB1ITGA5ITGB6 | |
| SCHEMBL21311663 | 0.75 | ITGAV (0.61) | ITGB3ITGAVITGB1ITGA5ITGB6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3538525-B1 | 3-SUBSTITUTED PROPIONIC ACIDS AS ALPHA V INTEGRIN INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2022-06-22 | — | — | EP | disclosed |
| WO-2018089353-A1 | 3-SUBSTITUTED PROPIONIC ACIDS AS ALPHA V INTEGRIN INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2018-05-17 | — | — | WO | disclosed |