Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1661090 | 0.79 | ADRB2 (0.35) | — | |
| SCHEMBL1661519 | 0.79 | UGT2B7 (0.39) | — | |
| SCHEMBL1661088 | 0.79 | ADRB2 (0.35) | — | |
| SCHEMBL1662054 | 0.79 | ADRB2 (0.35) | — | |
| SCHEMBL1031444 | 0.78 | LMNA (0.35) | TRPA1 | |
| SCHEMBL1068985 | 0.76 | TRPV4 (0.31) | — | |
| SCHEMBL3649949 | 0.71 | TRPA1 (0.42) | ABCB11TRPA1 | |
| SCHEMBL12891909 | 0.71 | ABCB11 (0.49) | ABCB11 | |
| SCHEMBL8653020 | 0.71 | ABCB11 (0.49) | ABCB11 | |
| SCHEMBL12284676 | 0.69 | HDAC4 (0.44) | ABCB11TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2513103-A1 | AZAINDOLE GLUCOKINASE ACTIVATORS | F. Hoffmann-La Roche AG (CH) | 2012-10-24 | — | — | EP | claimed |
| WO-2011073117-A1 | AZAINDOLE GLUCOKINASE ACTIVATORS | F. HOFFMANN-LA ROCHE AG (CH) | 2011-06-23 | — | — | WO | claimed |