Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.32 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20156071 | 0.79 | MPO (0.35) | — | |
| SCHEMBL20156351 | 0.76 | MPO (0.35) | — | |
| SCHEMBL20156337 | 0.76 | ITGB3 (0.48) | — | |
| SCHEMBL20156331 | 0.74 | MPO (0.37) | — | |
| SCHEMBL27406006 | 0.74 | MPO (0.38) | — | |
| SCHEMBL20156073 | 0.73 | FGFR4 (0.34) | MEN1KMT2A | |
| SCHEMBL20025181 | 0.72 | ITGAV (0.38) | — | |
| SCHEMBL25352180 | 0.71 | ITGAV (0.38) | — | |
| SCHEMBL31075928 | 0.69 | HSD11B1 (0.40) | — | |
| SCHEMBL29702271 | 0.69 | MPO (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3538527-B1 | AZOLE AMIDES AND AMINES AS ALPHA V INTEGRIN INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2021-10-13 | — | — | EP | disclosed |
| WO-2018089358-A1 | AZOLE AMIDES AND AMINES AS ALPHA V INTEGRIN INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2018-05-17 | — | — | WO | disclosed |