Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FASN | P49327 | 2/20 | 0.35 |
| ▸ | RORC | P51449 | 2/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | JAK1 | P23458 | 1/20 | 0.31 |
| ▸ | TYK2 | P29597 | 1/20 | 0.31 |
| ▸ | JAK3 | P52333 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20156411 | 0.84 | JAK2 (0.35) | FASNJAK2JAK1TYK2JAK3 | |
| SCHEMBL19559116 | 0.80 | KDM4E (0.46) | — | |
| SCHEMBL20156425 | 0.79 | JAK2 (0.32) | JAK2JAK1TYK2JAK3 | |
| SCHEMBL30410282 | 0.79 | GAA (0.43) | FASNRORC | |
| SCHEMBL23367734 | 0.77 | JAK2 (0.31) | JAK2JAK1TYK2JAK3 | |
| SCHEMBL20156488 | 0.76 | L3MBTL1 (0.36) | — | |
| SCHEMBL20156606 | 0.74 | FASN (0.37) | FASN | |
| SCHEMBL19113136 | 0.70 | KDM4E (0.37) | FASNRORC | |
| SCHEMBL23370244 | 0.68 | L3MBTL1 (0.33) | — | |
| SCHEMBL9674422 | 0.65 | RORC (0.39) | RORCAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089904-A1 | HETEROCYCLIC MODULATORS OF LIPID SYNTHESIS | 3-V BIOSCIENCES, INC. (US) | 2018-05-17 | — | — | WO | disclosed |