Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | MLYCD | O95822 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.32 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.31 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.31 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30969109 | 0.77 | SORT1 (0.37) | ALDH1A1SORT1HDAC1HDAC8HDAC6 | |
| SCHEMBL1553967 | 0.77 | SORT1 (0.37) | ALDH1A1SORT1HDAC1HDAC8HDAC6 | |
| SCHEMBL20157110 | 0.76 | HPGD (0.36) | TP53HPGDMLYCDALDH1A1LMNA | |
| SCHEMBL20157264 | 0.75 | TP53 (0.38) | TP53HPGDMLYCDALDH1A1LMNA | |
| SCHEMBL20157077 | 0.73 | TP53 (0.37) | TP53HPGDMLYCDALDH1A1LMNA | |
| SCHEMBL20156934 | 0.72 | HPGD (0.40) | TP53HPGDMLYCDALDH1A1LMNA | |
| SCHEMBL8282807 | 0.72 | MLYCD (0.39) | TP53HPGDMLYCDALDH1A1LMNA | |
| SCHEMBL18767254 | 0.70 | HPGD (0.51) | TP53HPGDMLYCDALDH1A1LMNA | |
| SCHEMBL29829214 | 0.69 | SORT1 (0.42) | HPGDALDH1A1LMNAKDM4ESORT1 | |
| SCHEMBL1363337 | 0.68 | PRSS1 (0.52) | TP53HPGDALDH1A1LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |