Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MLYCD | O95822 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20157023 | 0.76 | TP53 (0.35) | HPGDLMNASMN1; SMN2TP53MLYCD | |
| SCHEMBL22538519 | 0.75 | KCNH2 (0.38) | HPGDLMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL20156934 | 0.74 | HPGD (0.40) | HPGDLMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL20157098 | 0.72 | ALDH1A1 (0.32) | HPGDLMNATP53KDM4EALDH1A1 | |
| SCHEMBL8282807 | 0.71 | MLYCD (0.39) | HPGDLMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL22065201 | 0.69 | TDP1 (0.42) | HPGDMEN1KMT2ATSHRALDH1A1 | |
| SCHEMBL18432578 | 0.67 | PRSS1 (0.40) | HPGDLMNAKMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL22066370 | 0.67 | TDP1 (0.41) | HPGDLMNASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL18767254 | 0.66 | HPGD (0.51) | HPGDLMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL21078085 | 0.66 | TP53 (0.47) | HPGDLMNAMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |