Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28559337 | 0.76 | SORT1 (0.32) | — | |
| SCHEMBL20157110 | 0.72 | HPGD (0.36) | ALDH1A1LMNAKDM4EHPGDTP53 | |
| SCHEMBL22538519 | 0.70 | KCNH2 (0.38) | ALDH1A1LMNAHPGDTP53 | |
| SCHEMBL20157023 | 0.68 | TP53 (0.35) | ALDH1A1LMNAKDM4EHPGDTP53 | |
| SCHEMBL25938941 | 0.65 | APP (0.37) | ALDH1A1 | |
| SCHEMBL25940821 | 0.65 | CASP1 (0.33) | ALDH1A1LMNAKDM4EHPGD | |
| SCHEMBL20156934 | 0.63 | HPGD (0.40) | ALDH1A1LMNAKDM4EHPGDTP53 | |
| SCHEMBL8282807 | 0.62 | MLYCD (0.39) | ALDH1A1LMNAHPGDTP53 | |
| SCHEMBL28575095 | 0.62 | SORT1 (0.32) | — | |
| SCHEMBL23864603 | 0.62 | MAPT (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |