Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 7/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.43 |
| ▸ | DRD2 | P14416 | 2/20 | 0.41 |
| ▸ | DRD3 | P35462 | 2/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.39 |
| ▸ | HTR3A | P46098 | 2/20 | 0.39 |
| ▸ | HTR6 | P50406 | 2/20 | 0.39 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.39 |
| ▸ | HTR3B | O95264 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.39 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20141640 | 0.85 | HTR1A (0.40) | HTR1ASLC6A2SLC6A4SLC6A3DRD2 | |
| SCHEMBL20157160 | 0.80 | DRD2 (0.53) | HTR1ASLC6A2SLC6A4SLC6A3DRD2 | |
| SCHEMBL20141638 | 0.77 | HTR1A (0.41) | HTR1ASLC6A2SLC6A4SLC6A3DRD2 | |
| SCHEMBL6990507 | 0.74 | DRD2 (0.48) | HTR1ASLC6A2SLC6A4SLC6A3DRD2 | |
| SCHEMBL6809963 | 0.74 | MC4R (0.42) | HTR1ASLC6A2SLC6A4SLC6A3DRD2 | |
| SCHEMBL20142226 | 0.74 | BRPF1 (0.35) | DRD2ADRB1LMNA | |
| SCHEMBL27499765 | 0.73 | ALOX5 (0.56) | HTR1ASLC6A2SLC6A4SLC6A3DRD3 | |
| SCHEMBL7800659 | 0.73 | HTR1A (0.55) | HTR1ASLC6A2SLC6A4SLC6A3DRD2 | |
| SCHEMBL8370464 | 0.72 | HTR1A (0.54) | HTR1ASLC6A2SLC6A4SLC6A3DRD2 | |
| SCHEMBL6220020 | 0.72 | HTR1A (0.54) | HTR1ASLC6A2SLC6A4SLC6A3DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |