Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 7/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 2/20 | 0.46 |
| ▸ | DRD4 | P21917 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20157021 | 0.91 | SLC6A7 (0.46) | GBA1KDM4EALDH1A1NPSR1SLC6A7 | |
| SCHEMBL20157037 | 0.87 | SLC6A7 (0.52) | GBA1KDM4ESLC6A7HPGD | |
| SCHEMBL20141809 | 0.83 | GBA1 (0.44) | GBA1KDM4EALDH1A1NPSR1DRD4 | |
| SCHEMBL20140693 | 0.81 | HCRTR1 (0.49) | GBA1KDM4EALDH1A1NPSR1 | |
| SCHEMBL20156911 | 0.80 | KDM4E (0.55) | KDM4EALDH1A1NPSR1ATMDRD2 | |
| SCHEMBL20140044 | 0.77 | MTOR (0.54) | KDM4EALDH1A1NPSR1DRD2DRD4 | |
| SCHEMBL20157290 | 0.77 | MTOR (0.50) | KDM4EALDH1A1NPSR1ATMDRD2 | |
| SCHEMBL20140472 | 0.76 | PARP1 (0.46) | GBA1KDM4EALDH1A1 | |
| SCHEMBL20157539 | 0.76 | MTOR (0.46) | KDM4EALDH1A1NPSR1DRD4HPGD | |
| SCHEMBL20140785 | 0.76 | PARP1 (0.47) | KDM4EALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |