SCHEMBL20157585

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL11857823	0.89	APLNR (0.44)	LMNATHRATHRBMTNR1AMTNR1B
	SCHEMBL20157583	0.86	LMNA (0.46)	LMNAADRA2AADRA1ACYP2D6KMT2A
	SCHEMBL18113374	0.85	LMNA (0.45)	LMNAMTNR1AMTNR1BADRA2AADRA1A
	SCHEMBL23457049	0.84	ADRA2A (0.47)	LMNAADRA2AADRA1AHPGDCYP2D6
	SCHEMBL31682604	0.84	ADRA2A (0.47)	LMNAADRA2AADRA1AHPGDCYP2D6
	SCHEMBL30057731	0.80	AOC3 (0.47)	LMNAADRA2AADRA1ACYP2D6MAPK1
	SCHEMBL20157837	0.80	ACHE (0.39)	LMNATHRATHRBKMT2ANFE2L2
	SCHEMBL13427765	0.78	NFE2L2 (0.53)	LMNAGAAHPGDCYP2D6KMT2A
	SCHEMBL21362021	0.78	ACHE (0.38)	LMNATHRATHRBGAANFE2L2
	SCHEMBL20157860	0.77	PDE10A (0.38)	LMNATHRATHRBGAAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.