SCHEMBL20158025

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL20157569	0.85	CES2 (0.41)	KMT2A
	SCHEMBL20157512	0.84	NPC1 (0.46)	NPC1SMN1; SMN2RAB9AFFAR4FFAR1
	SCHEMBL20157769	0.83	HPGD (0.39)	NPC1RAB9AKMT2APYGL
	SCHEMBL20158044	0.82	NPC1 (0.35)	NPC1RAB9AKDM4EMAPTPYGL
	SCHEMBL21352105	0.82	ACHE (0.47)	SMN1; SMN2RAB9AKDM4EMAPT
	SCHEMBL20157679	0.82	ALDH1A1 (0.40)	SMN1; SMN2MAPT
	SCHEMBL20157579	0.82	TP53 (0.38)	SMN1; SMN2KDM4EMAPTKMT2A
	SCHEMBL21550074	0.81	KMT2A (0.40)	KMT2APPARG
	SCHEMBL20157485	0.78	ALDH1A1 (0.41)	NPC1MAPTKMT2A
	SCHEMBL21555624	0.78	KMT2A (0.33)	CDK1CDK4CCND1CDK2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.