SCHEMBL20157512

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL20157513	0.87	NPC1 (0.46)	NPC1SMN1; SMN2RAB9AFFAR4FFAR1
	SCHEMBL21362429	0.85	SMN1; SMN2 (0.41)	NPC1SMN1; SMN2RAB9AFFAR4FFAR1
	SCHEMBL20158023	0.85	ABL1 (0.45)	NPC1SMN1; SMN2RAB9AMEN1KMT2A
	SCHEMBL20158025	0.84	NPC1 (0.42)	NPC1SMN1; SMN2RAB9AFFAR4FFAR1
	SCHEMBL20157850	0.84	MAPT (0.39)	NPC1SMN1; SMN2RAB9AFFAR4FFAR1
	SCHEMBL20158157	0.82	KMT2A (0.41)	NPC1SMN1; SMN2RAB9AMEN1KMT2A
	SCHEMBL20157777	0.82	CES2 (0.47)	KMT2ANR3C1
	SCHEMBL27709578	0.81	NPC1 (0.51)	NPC1SMN1; SMN2RAB9AFFAR4FFAR1
	SCHEMBL21362819	0.81	ACHE (0.40)	NPC1SMN1; SMN2RAB9AKMT2ALCK
	SCHEMBL20157984	0.81	NPC1 (0.38)	NPC1SMN1; SMN2RAB9AMAPTLCK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.