Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 3/20 | 0.32 |
| ▸ | GNAO1 | P09471 | 3/20 | 0.32 |
| ▸ | GNAI1 | P63096 | 3/20 | 0.32 |
| ▸ | NCF1 | P14598 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18782820 | 0.80 | GNAI3 (0.37) | GNAI3GNAO1GNAI1 | |
| SCHEMBL800830 | 0.77 | NCF1 (0.33) | NCF1 | |
| SCHEMBL19388438 | 0.70 | CHRNB4 (0.40) | GNAI3GNAO1GNAI1 | |
| SCHEMBL13185832 | 0.69 | GNAI3 (0.40) | GNAI3GNAO1GNAI1NCF1 | |
| SCHEMBL20880180 | 0.69 | NCF1 (0.38) | GNAI3GNAO1GNAI1NCF1 | |
| SCHEMBL18470452 | 0.69 | NCF1 (0.38) | GNAI3GNAO1GNAI1NCF1 | |
| SCHEMBL19993220 | 0.68 | — | — | |
| SCHEMBL19928673 | 0.68 | CCNT1 (0.36) | NCF1 | |
| SCHEMBL6027356 | 0.67 | NCF1 (0.37) | GNAI3GNAO1GNAI1NCF1 | |
| SCHEMBL13772759 | 0.66 | NCF1 (0.39) | GNAI3GNAO1GNAI1NCF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180134690-A1 | INDAZOLES AND USE THEREOF | PURDUE PHARMA LP (US) | 2018-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180134690-A1 | INDAZOLES AND USE THEREOF | TRPV3, TRPA1, TRPV1 | GNAI3 159/4885GNAO1 594/4885GNAI1 313/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.