Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | KDM5A | P29375 | 1/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21303553 | 0.83 | PKM (0.47) | KDM4ERAB9AHPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL24053056 | 0.79 | HPGD (0.43) | KDM4ERAB9AHPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL12290381 | 0.78 | SOD1 (0.43) | RAB9AHPGDSMN1; SMN2PKMPOLB | |
| SCHEMBL23310017 | 0.76 | IDH1 (0.42) | KDM4ERAB9AHPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL23062777 | 0.76 | UNG (0.41) | KDM4ERAB9AHPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL12290364 | 0.76 | SOD1 (0.48) | RAB9ASMN1; SMN2ALDH1A1GPR84KDM5A | |
| SCHEMBL25409550 | 0.75 | SMN1; SMN2 (0.43) | KDM4ERAB9AHPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL12289980 | 0.75 | KDM5A (0.42) | KDM4ERAB9AHPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL23062794 | 0.75 | KDM4E (0.45) | KDM4ERAB9AHPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL23271254 | 0.75 | KDM4E (0.43) | KDM4ERAB9AHPGDSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230066830-A1 | METHODS AND COMPOSITIONS FOR INDUCING APOPTOSIS IN CANCER STEM CELLS | UNIV VIRGINIA COMMONWEALTH (US) | 2023-03-02 | — | — | US | disclosed |
| US-20210214365-A1 | INHIBITORS OF CANCER INVASION, ATTACHMENT, AND/OR METASTASIS | Sanford Burnham Prebys Medical Discovery Institute | 2021-07-15 | — | — | US | disclosed |
| WO-2021127305-A1 | METHODS AND COMPOSITIONS FOR INDUCING APOPTOSIS IN CANCER STEM CELLS | VIRGINIA COMMONWEALTH UNIVERSITY (US) | 2021-06-24 | — | — | WO | disclosed |
| US-11008325-B2 | Inhibitors of cancer invasion, attachment, and/or metastasis | VIRGINIA COMMONWEALTH UNIVERSITY (US) | 2021-05-18 | — | — | US | disclosed |
| US-20190263824-A1 | INHIBITORS OF CANCER INVASION, ATTACHMENT, AND/OR METASTASIS | VIRGINIA COMMONWEALTH UNIVERSITY | 2019-08-29 | — | — | US | disclosed |
| WO-2018089967-A1 | INHIBITORS OF CANCER INVASION, ATTACHMENT, AND/OR METASTASIS | VIRGINIA COMMONWEALTH UNIVERSITY (US) | 2018-05-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210214365-A1 | INHIBITORS OF CANCER INVASION, ATTACHMENT, AND/OR METASTASIS | SDCBP, SDC1, SDAD1 | KDM4E 3578/4885RAB9A 261/4885HPGD 4472/4885 |
| US-20190263824-A1 | INHIBITORS OF CANCER INVASION, ATTACHMENT, AND/OR METASTASIS | SDCBP, SDC1, SDAD1 | KDM4E 3578/4885RAB9A 261/4885HPGD 4472/4885 |
| US-20230066830-A1 | METHODS AND COMPOSITIONS FOR INDUCING APOPTOSIS IN CANCER STEM CELLS | SDCBP, BAX, MCL1 | KDM4E 3648/4885RAB9A 305/4885HPGD 3278/4885 |
| US-11008325-B2 | Inhibitors of cancer invasion, attachment, and/or metastasis | SDCBP, SDC1, SDAD1 | KDM4E 3578/4885RAB9A 261/4885HPGD 4472/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.