Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 1/20 | 0.42 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | ALPG | P10696 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
| ▸ | GRK2 | P25098 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
| ▸ | NOS1 | P29475 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ALPL | P05186 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23062752 | 0.87 | ACKR3 (0.42) | ALDH1A1HPGDKDM4ERAB9AMAPK10 | |
| SCHEMBL23062732 | 0.86 | KDM4E (0.41) | ALDH1A1HPGDKDM4ERAB9AMAPK10 | |
| SCHEMBL23310186 | 0.83 | MAPT (0.41) | ALDH1A1HPGDKDM4ERAB9AMAPK10 | |
| SCHEMBL23271259 | 0.83 | RAB9A (0.41) | ALDH1A1HPGDKDM4ERAB9AMAPK10 | |
| SCHEMBL23062819 | 0.81 | SMN1; SMN2 (0.41) | ALDH1A1HPGDKDM4ERAB9AMAPK10 | |
| SCHEMBL23062720 | 0.81 | KDM4E (0.39) | IDH1ALDH1A1HPGDKDM4ERAB9A | |
| SCHEMBL23062809 | 0.81 | BCAT2 (0.43) | ALDH1A1HPGDKDM4ERAB9AMAPK10 | |
| SCHEMBL23271256 | 0.81 | SMN1; SMN2 (0.41) | ALDH1A1HPGDKDM4ERAB9AMAPK10 | |
| SCHEMBL23062777 | 0.80 | UNG (0.41) | ALDH1A1HPGDKDM4ERAB9AMAPK10 | |
| SCHEMBL23310020 | 0.79 | ALDH1A1 (0.38) | ALDH1A1HPGDKDM4ERAB9AMAPK10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210121465-A1 | FERROCHELATASE INHIBITORS AND METHODS OF USE | GACHON UNIVERSITY OF INDUSTRY-ACADEMIC COOPERATION FOUNDATION (KR) | 2021-04-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210121465-A1 | FERROCHELATASE INHIBITORS AND METHODS OF USE | FECH, SLC40A1, TPI1 | IDH1 117/4885DCTPP1 293/4885ALDH1A1 701/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.