Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL709825 | 0.83 | TDP1 (0.42) | KMT2AMEN1TDP1HSD17B10TSHR | |
| SCHEMBL8374 | 0.75 | TDP1 (0.54) | KMT2AMEN1TDP1HSD17B10TSHR | |
| SCHEMBL667879 | 0.74 | TDP1 (0.44) | KMT2AMEN1TDP1HSD17B10TSHR | |
| SCHEMBL8011477 | 0.73 | ALDH1A1 (0.43) | KMT2AMEN1TDP1HSD17B10TSHR | |
| SCHEMBL33832 | 0.72 | TDP1 (0.46) | KMT2AMEN1TDP1HSD17B10TSHR | |
| SCHEMBL7136437 | 0.72 | TDP1 (0.46) | KMT2AMEN1TDP1HSD17B10TSHR | |
| SCHEMBL15639404 | 0.71 | ALDH1A1 (0.46) | KMT2AMEN1TDP1HSD17B10ALDH1A1 | |
| SCHEMBL2075134 | 0.71 | TDP1 (0.45) | KMT2AMEN1TDP1HSD17B10TSHR | |
| SCHEMBL1036583 | 0.71 | TDP1 (0.45) | KMT2AMEN1TDP1HSD17B10TSHR | |
| SCHEMBL7907932 | 0.71 | TDP1 (0.45) | KMT2AMEN1TDP1HSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2516517-B1 | BLOWN GRADE SHOWING SUPERIOR STIFFNESS, TRANSPARENCY AND PROCESSING BEHAVIOUR | BOREALIS AG (AT) | 2017-06-21 | — | — | EP | disclosed |
| EP-2867294-B1 | HIGH MELT STRENGTH POLYPROPYLENE OF IMPROVED QUALITY | BOREALIS AG (AT) | 2017-05-17 | — | — | EP | disclosed |
| WO-2017068088-A1 | HETEROPHASIC COMPOSITION | BOREALIS AG (AT) | 2017-04-27 | — | — | WO | disclosed |
| EP-2867294-A1 | HIGH MELT STRENGTH POLYPROPYLENE OF IMPROVED QUALITY | Borealis AG (AT) | 2015-05-06 | — | — | EP | disclosed |
| WO-2014001394-A1 | HIGH MELT STRENGTH POLYPROPYLENE OF IMPROVED QUALITY | BOREALIS AG (AT) | 2014-01-03 | — | — | WO | disclosed |
| EP-2516517-A2 | BLOWN GRADE SHOWING SUPERIOR STIFFNESS, TRANSPARENCY AND PROCESSING BEHAVIOUR | Borealis AG (AT) | 2012-10-31 | — | — | EP | disclosed |
| WO-2011076637-A2 | BLOWN GRADE SHOWING SUPERIOR STIFFNESS, TRANSPARENCY AND PROCESSING BEHAVIOUR | BOREALIS AG (AT) | 2011-06-30 | — | — | WO | disclosed |