Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | S100A4 | P26447 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11473400 | 0.85 | ALDH1A1 (0.46) | TDP1HSD17B10KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL8374 | 0.75 | TDP1 (0.54) | TDP1HSD17B10TSHRKMT2AMEN1 | |
| SCHEMBL2016086 | 0.74 | KMT2A (0.44) | TDP1HSD17B10TSHRKMT2AMEN1 | |
| SCHEMBL33832 | 0.72 | TDP1 (0.46) | TDP1HSD17B10TSHRKMT2AMEN1 | |
| SCHEMBL7136437 | 0.72 | TDP1 (0.46) | TDP1HSD17B10TSHRKMT2AMEN1 | |
| SCHEMBL709825 | 0.72 | TDP1 (0.42) | TDP1HSD17B10TSHRKMT2AMEN1 | |
| SCHEMBL2075134 | 0.71 | TDP1 (0.45) | TDP1HSD17B10TSHRKMT2AMEN1 | |
| SCHEMBL7907932 | 0.71 | TDP1 (0.45) | TDP1HSD17B10TSHRKMT2AMEN1 | |
| SCHEMBL1179577 | 0.71 | TDP1 (0.45) | TDP1HSD17B10TSHRKMT2AMEN1 | |
| SCHEMBL41322 | 0.71 | GPR35 (0.54) | TDP1HSD17B10TSHRKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012024558-A2 | LIGHT MEDIATED REGULATION OF PROTEIN DIMERIZATION | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2012-02-23 | — | — | WO | disclosed |
| US-4256458-A | DIMERIC PYRIDINIUM DYES | BASF AKTIENGESELLSCHAFT (DE) | 1981-03-17 | — | — | US | disclosed |