Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 2/20 | 0.44 |
| ▸ | FNTB | P49356 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MPI | P34949 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | SMO | Q99835 | 4/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2011899 | 0.93 | ALDH1A1 (0.44) | NPSR1KMT2AMEN1CYP1A2CYP3A4 | |
| SCHEMBL2013450 | 0.91 | IDE (0.45) | NPSR1KMT2AMEN1CYP1A2CYP3A4 | |
| SCHEMBL2014599 | 0.88 | FNTA (0.44) | FNTAFNTBNPSR1KMT2AMEN1 | |
| SCHEMBL2164834 | 0.84 | FNTA (0.47) | FNTAFNTBNPSR1KMT2AMEN1 | |
| SCHEMBL2164175 | 0.81 | FNTA (0.44) | FNTAFNTBNPSR1KMT2AMEN1 | |
| SCHEMBL2019485 | 0.80 | SMO (0.49) | NPSR1KMT2AMEN1CYP1A2CYP3A4 | |
| SCHEMBL2012195 | 0.80 | ALDH1A1 (0.44) | NPSR1KMT2AMEN1CYP1A2CYP3A4 | |
| SCHEMBL2013930 | 0.80 | AKR1C3 (0.43) | NPSR1KMT2AMEN1CYP1A2CYP2C19 | |
| SCHEMBL2016804 | 0.80 | SLC6A7 (0.47) | NPSR1KMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL2014280 | 0.79 | MEN1 (0.52) | KMT2AMEN1CYP3A4CYP2C19ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011075630-A1 | SUBSTITUTED FUSED ARYL AND HETEROARYL DERIVATIVES AS PI3K INHIBITORS | INCYTE CORPORATION (US) | 2011-06-23 | — | — | WO | disclosed |