Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Adipic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 8/20 | 0.54 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.54 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 5/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.48 |
| ▸ | PPARG | P37231 | 6/20 | 0.46 |
| ▸ | PPARD | Q03181 | 6/20 | 0.46 |
| ▸ | PPARA | Q07869 | 6/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | TLR2 | O60603 | 2/20 | 0.46 |
| ▸ | FABP4 | P15090 | 2/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.46 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.46 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Adipic Acid SCHEMBL15632806 | 0.96 | GPR84 (0.50) | GPR84FFAR1FFAR4LMNACAMK2A | |
| Adipic Acid SCHEMBL27922095 | 0.95 | LMNA (0.58) | GPR84FFAR1FFAR4LMNATSHR | |
| Adipic Acid SCHEMBL10936251 | 0.95 | LMNA (0.58) | GPR84FFAR1FFAR4LMNATSHR | |
| Adipic Acid SCHEMBL346488 | 0.95 | LMNA (0.58) | GPR84FFAR1FFAR4LMNATSHR | |
| Adipic Acid SCHEMBL6282986 | 0.93 | GPR84 (0.65) | GPR84FFAR1FFAR4LMNACAMK2A | |
| Sebacic Acid SCHEMBL347212 | 0.93 | TSHR (0.60) | GPR84FFAR1FFAR4LMNATSHR | |
| Propylene Glycol SCHEMBL5035967 | 0.93 | TSHR (0.60) | GPR84FFAR1FFAR4LMNATSHR | |
| Azelaic Acid SCHEMBL347853 | 0.93 | TSHR (0.60) | GPR84FFAR1FFAR4LMNATSHR | |
| Adipic Acid SCHEMBL28436413 | 0.93 | LMNA (0.55) | GPR84FFAR1FFAR4LMNATSHR | |
| Octanedioate SCHEMBL28872523 | 0.93 | TSHR (0.60) | GPR84FFAR1FFAR4LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 146 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117624877-A | Transparent high-toughness modified polyurethane material and preparation method and application thereof | 河南驼人医疗器械集团有限公司 | 2024-03-01 | — | — | CN | claimed |
| CN-115710368-B | Surface spraying GPU protective layer, light wear-resisting foaming sole | 茂泰(福建)新材料科技有限公司 | 2023-09-19 | — | — | CN | claimed |
| CN-116003697-A | Polyurethane interpenetrating network polishing pad for aviation organic glass polishing and preparation method thereof | 锦西化工研究院有限公司 | 2023-04-25 | — | — | CN | claimed |
| CN-115710368-A | Light and wear-resistant foamed sole with GPU (graphics processing Unit) protective layer sprayed on surface | 茂泰(福建)鞋材有限公司 | 2023-02-24 | — | — | CN | claimed |
| CN-115141479-B | Modified TPU for encapsulating PC and preparation method thereof | 山东一诺威聚氨酯股份有限公司 | 2023-01-31 | — | — | CN | claimed |
| CN-115625921-A | Method for integrally compounding and molding pattern GPU negative film and polyurethane insole | 茂泰(福建)鞋材有限公司 | 2023-01-20 | — | — | CN | claimed |
| CN-113185662-B | Low-temperature-resistant ultraviolet-aging-resistant thermoplastic polyurethane elastomer and preparation method thereof | 郑州大学 | 2022-07-26 | — | — | CN | claimed |
| CN-113185662-A | Low-temperature-resistant ultraviolet-aging-resistant thermoplastic polyurethane elastomer and preparation method thereof | 郑州大学 | 2021-07-30 | — | — | CN | claimed |
| CN-109456459-B | Method for improving water resistance or solvent resistance of waterborne polyurethane | 中国科学院山西煤炭化学研究所 | 2021-06-29 | — | — | CN | claimed |
| CN-112480353-A | Super-oil-resistant heat-resistant TPU material and preparation method thereof | 山东一诺威聚氨酯股份有限公司 | 2021-03-12 | — | — | CN | claimed |
| CN-110204681-B | Preparation method of self-healing fluorescent polyurethane film containing imidazolidinyl urea at hard segment | 西安交通大学 | 2020-09-01 | — | — | CN | claimed |
| CN-110218290-B | Synthetic method of tough, transparent, fluorescent and antibacterial polyurethane film | 西安交通大学 | 2020-08-04 | — | — | CN | claimed |
| CN-111073582-A | Preparation method of microprism coating adhesive | 常州华日升反光材料有限公司 | 2020-04-28 | — | — | CN | claimed |
| CN-110862506-A | Synthetic method of waterborne polyurethane primer | 中国科学院山西煤炭化学研究所 | 2020-03-06 | — | — | CN | claimed |
| CN-106750133-B | Low hardness polyurethane rubber roller material and preparation method thereof | 山东一诺威聚氨酯股份有限公司 | 2019-08-16 | — | — | CN | claimed |
| EP-1971427-A1 | VISIBLE LIGHT CURING SYSTEMS, METHODS FOR REDUCING HEALTH RISKS TO INDIVIDUALS EXPOSED TO SYSTEMS DESIGNED TO CURE CURABLE COMPOSITIONS BY EXPOSURE TO RADIATION, METHODS FOR BONDING SUBSTRATES AND VISIBLE LIGHT CURING COMPOSITIONS | Henkel Corporation (US) | 2008-09-24 | — | — | EP | claimed |
| WO-2007078851-A1 | VISIBLE LIGHT CURING SYSTEMS, METHODS FOR REDUCING HEALTH RISKS TO INDIVIDUALS EXPOSED TO SYSTEMS DESIGNED TO CURE CURABLE COMPOSITIONS BY EXPOSURE TO RADIATION, METHODS FOR BONDING SUBSTRATES AND VISIBLE LIGHT CURING COMPOSITIONS | HENKEL CORPORATION (US) | 2007-07-12 | — | — | WO | claimed |
| CN-107922561-B | Polyurethane resin particles | 关西涂料株式会社 | 2024-07-12 | — | — | CN | disclosed |
| US-3956200-A | POLYGLYCOL HYDROGEN POLYPHOSPHONATE | STAUFFER CHEMICAL COMPANY (US) | 1976-05-11 | — | — | US | disclosed |
| US-3933696-A | Polyalkylene glycol poly-phosphorus compounds in polyurethane foams | STAUFFER CHEMICAL COMPANY (US) | 1976-01-20 | — | — | US | disclosed |