SCHEMBL20164147

SCHEMBL20164147

OB(O)c1ccc(Cl)cc1-c1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGDR2 Q9Y5Y4 1/20 0.45
KMT2A Q03164 4/20 0.44
MEN1 O00255 3/20 0.44
RXFP1 Q9HBX9 1/20 0.44
CYP1A2 P05177 1/20 0.41
S100A4 P26447 1/20 0.41
OPRK1 P41145 2/20 0.41
NR1I2 O75469 1/20 0.41
ADORA3 P0DMS8 1/20 0.41
HTR2C P28335 1/20 0.41
ADRA1A P35348 1/20 0.41
PTGS2 P35354 1/20 0.41
CHRNA4 P43681 1/20 0.41
SLC6A3 Q01959 1/20 0.41
PDE4D Q08499 1/20 0.41
MAPK1 P28482 2/20 0.41
CHRM1 P11229 5/20 0.40
LMNA P02545 3/20 0.40
PDE3A Q14432 1/20 0.40
BACE1 P56817 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3110322 0.85 KMT2A (0.44) PTGDR2KMT2AMEN1RXFP1CYP1A2
SCHEMBL12539016 0.82 MEN1 (0.41) KMT2AMEN1
SCHEMBL13642178 0.80 MGLL (0.50) KMT2AMEN1PTGS2LMNABACE1
SCHEMBL31576793 0.80 MGLL (0.50) KMT2AMEN1PTGS2LMNABACE1
SCHEMBL19464511 0.78 HDAC7 (0.49) PTGDR2KMT2AMEN1CHRM1LMNA
SCHEMBL3106470 0.78 MAP2 (0.43) KMT2AMEN1CYP1A2S100A4HTR2C
SCHEMBL25320059 0.77 PTGDR2 (0.45) PTGDR2MAPK1LMNABACE1MAPT
SCHEMBL28489366 0.77 BACE1 (0.40) KMT2AMEN1CYP1A2HTR2CPTGS2
SCHEMBL28545275 0.77 METAP2 (0.37) PTGDR2KMT2AMEN1RXFP1CYP1A2
SCHEMBL29664280 0.76 SLC6A4 (0.47) KMT2AMEN1CYP1A2PTGS2SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025135767-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME 솔루스첨단소재 주식회사 2025-06-26 WO disclosed
US-20240373745-A1 COMPOUND, ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2024-11-07 US disclosed
CN-116444435-B Fluorene derivative, electronic element and electronic device 浙江八亿时空先进材料有限公司 2024-05-24 CN disclosed
CN-116444435-A Fluorene derivative, electronic element and electronic device 浙江八亿时空先进材料有限公司 2023-07-18 CN disclosed
US-20230183191-A1 NITROGEN-CONTAINING COMPOUND, ELECTRONIC ELEMENT, AND ELECTRONIC DEVICE SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2023-06-15 US disclosed
US-20230183191-A1 NITROGEN-CONTAINING COMPOUND, ELECTRONIC ELEMENT, AND ELECTRONIC DEVICE SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2023-06-15 US disclosed
WO-2022262365-A1 ORGANIC COMPOUND, AND ELECTRONIC ELEMENT AND ELECTRONIC DEVICE COMPRISING SAME 陕西莱特光电材料股份有限公司 2022-12-22 WO disclosed
US-10833276-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2020-11-10 US disclosed
US-20180145262-A1 Organic Electroluminescent Materials and Devices UNIVERSAL DISPLAY CORPORATION 2018-05-24 US disclosed
US-20180145262-A1 Organic Electroluminescent Materials and Devices UNIVERSAL DISPLAY CORPORATION 2018-05-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10833276-B2 Organic electroluminescent materials and devices OCIAD2, OCIAD1, TYR PTGDR2 4334/4885KMT2A 3047/4885MEN1 4256/4885
US-20230183191-A1 NITROGEN-CONTAINING COMPOUND, ELECTRONIC ELEMENT, AND ELECTRONIC DEVICE CNOT1, NXF1, NR2E1 PTGDR2 2680/4885KMT2A 2134/4885MEN1 1030/4885
US-20180145262-A1 Organic Electroluminescent Materials and Devices OCIAD2, OCIAD1, TYR PTGDR2 4334/4885KMT2A 3047/4885MEN1 4256/4885
US-20240373745-A1 COMPOUND, ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE RER1, RPS19, ESRRA PTGDR2 1057/4885KMT2A 1538/4885MEN1 1012/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.