Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20164298 | 0.86 | LMNA (0.41) | MAPTNPC1RAB9AALDH1A1L3MBTL1 | |
| SCHEMBL18249467 | 0.85 | TAS1R3 (0.36) | MAPTNPC1RAB9AALDH1A1TAS1R3 | |
| SCHEMBL16555821 | 0.80 | TAS1R3 (0.40) | MAPTNPC1RAB9AALDH1A1TAS1R3 | |
| SCHEMBL20164227 | 0.78 | ALDH1A1 (0.49) | MAPTNPC1RAB9AALDH1A1L3MBTL1 | |
| SCHEMBL18249399 | 0.76 | MAPT (0.38) | MAPTNPC1RAB9AALDH1A1TAS1R3 | |
| SCHEMBL18249486 | 0.76 | ACHE (0.44) | MAPTNPC1RAB9AALDH1A1TAS1R3 | |
| SCHEMBL20164216 | 0.76 | ALDH1A1 (0.52) | MAPTNPC1RAB9AALDH1A1L3MBTL1 | |
| SCHEMBL571227 | 0.75 | CA1 (0.63) | ALDH1A1L3MBTL1KMT2ACA12CA1 | |
| SCHEMBL17924097 | 0.74 | RARB (0.42) | NPC1RAB9AALDH1A1ESR1SMN1; SMN2 | |
| SCHEMBL18249448 | 0.74 | CYP4F2 (0.41) | MAPTNPC1RAB9AALDH1A1TAS1R3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3298048-B1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA SRL (IT) | 2019-07-03 | — | — | EP | disclosed |
| US-10221256-B2 | Catalyst components for the polymerization of olefins | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2019-03-05 | — | — | US | disclosed |
| US-20180142044-A1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2018-05-24 | — | — | US | disclosed |