SCHEMBL20164477

SCHEMBL20164477

CCCNc1nc(NC)c2nc(CNCC(C)(C)O)nc(NC)c2n1

nearest known ligand 0.38

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
SLC29A1 Q99808 1/20 0.38
KMT2A Q03164 1/20 0.33
APP P05067 1/20 0.32
BCHE P06276 1/20 0.32
ACHE P22303 1/20 0.32
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
CA9 Q16790 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL20164693 0.99 SLC29A1 (0.37) SLC29A1KMT2AAPPBCHEACHE
SCHEMBL20164406 0.85 SLC29A1 (0.44) SLC29A1KMT2AAPPBCHEACHE
Hydrochloric Acid SCHEMBL20164717 0.84 SLC29A1 (0.43) SLC29A1KMT2AAPPBCHEACHE
SCHEMBL16127987 0.78 SLC29A1 (0.42) SLC29A1KMT2AAPPBCHEACHE
SCHEMBL20164518 0.78 SLC29A1 (0.38) SLC29A1
SCHEMBL16094704 0.78 SLC29A1 (0.51) SLC29A1KMT2AAPPBCHEACHE
Hydrochloric Acid SCHEMBL20164531 0.77 SLC29A1 (0.37) SLC29A1
Hydrochloric Acid SCHEMBL16094696 0.76 SLC29A1 (0.50) SLC29A1KMT2AAPPBCHEACHE
SCHEMBL16094427 0.75 SLC29A1 (0.47) SLC29A1KMT2AAPPBCHEACHE
SCHEMBL20164475 0.74 SLC29A1 (0.44) SLC29A1KMT2AAPPBCHEACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180141953-A1 Novel Breathing Control Modulating Compounds, and Methods of Making and Using Same NEURAD LTD. (IL) 2018-05-24 US claimed
US-20250057848-A1 GAL475 COMPOSITIONS AND METHODS OF USE THEREOF NEURIM PHARMACEUTICALS (1991) LTD. (IL) 2025-02-20 US disclosed
EP-3316890-B1 NOVEL BREATHING CONTROL MODULATING COMPOUNDS, AND METHODS OF MAKING AND USING SAME NEURAD LTD (IL) 2023-09-06 EP disclosed
US-10294228-B2 Breathing control modulating compounds, and methods of making and using same NEURAD LTD. (IL) 2019-05-21 US disclosed
US-20180141953-A1 Novel Breathing Control Modulating Compounds, and Methods of Making and Using Same NEURAD LTD. (IL) 2018-05-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180141953-A1 Novel Breathing Control Modulating Compounds, and Methods of Making and Using Same MTNR1B, CHRM3, PER2 SLC29A1 4472/4885KMT2A 2456/4885APP 2716/4885
US-20250057848-A1 GAL475 COMPOSITIONS AND METHODS OF USE THEREOF GPR119, GPR35, GPR55 SLC29A1 2077/4885KMT2A 1865/4885APP 622/4885
US-10294228-B2 Breathing control modulating compounds, and methods of making and using same MTNR1B, PDE3A, CHRM3 SLC29A1 4518/4885KMT2A 2528/4885APP 2394/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.