SCHEMBL20164624

SCHEMBL20164624

CCCNc1nc(NC)nc2c(NC[C@H](C)O)nc(NC)nc12

nearest known ligand 0.44

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
SLC29A1 Q99808 6/20 0.44
CDK2 P24941 4/20 0.34
CCNE1 P24864 3/20 0.34
TLR7 Q9NYK1 1/20 0.34
CDK1 P06493 3/20 0.34
CSNK2A2 P19784 1/20 0.33
CSNK2B P67870 1/20 0.33
CSNK2A1 P68400 1/20 0.33
CDK7 P50613 1/20 0.32
CDK9 P50750 1/20 0.32
CDK5 Q00535 1/20 0.32
APP P05067 1/20 0.31
BCHE P06276 1/20 0.31
ACHE P22303 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20164310 1.00 SLC29A1 (0.44) SLC29A1CDK2CCNE1TLR7CDK1
SCHEMBL20164496 1.00 SLC29A1 (0.44) SLC29A1CDK2CCNE1TLR7CDK1
Hydrochloric Acid SCHEMBL20164587 0.98 SLC29A1 (0.43) SLC29A1CDK2CCNE1TLR7CDK1
Hydrochloric Acid SCHEMBL20164585 0.98 SLC29A1 (0.43) SLC29A1CDK2CCNE1TLR7CDK1
Hydrochloric Acid SCHEMBL20164674 0.98 SLC29A1 (0.43) SLC29A1CDK2CCNE1TLR7CDK1
SCHEMBL18360939 0.92 SLC29A1 (0.39) SLC29A1CDK2CCNE1TLR7APP
SCHEMBL31400311 0.88 SLC29A1 (0.43) SLC29A1TLR7APPBCHEACHE
SCHEMBL20164371 0.87 SLC29A1 (0.43) SLC29A1TLR7APPBCHEACHE
Hydrochloric Acid SCHEMBL20164604 0.85 SLC29A1 (0.42) SLC29A1TLR7APPBCHEACHE
SCHEMBL20164616 0.85 SLC29A1 (0.46) SLC29A1CDK2CCNE1TLR7CDK9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180141953-A1 Novel Breathing Control Modulating Compounds, and Methods of Making and Using Same NEURAD LTD. (IL) 2018-05-24 US claimed
US-20250057848-A1 GAL475 COMPOSITIONS AND METHODS OF USE THEREOF NEURIM PHARMACEUTICALS (1991) LTD. (IL) 2025-02-20 US disclosed
EP-3316890-B1 NOVEL BREATHING CONTROL MODULATING COMPOUNDS, AND METHODS OF MAKING AND USING SAME NEURAD LTD (IL) 2023-09-06 EP disclosed
EP-3316890-B1 NOVEL BREATHING CONTROL MODULATING COMPOUNDS, AND METHODS OF MAKING AND USING SAME NEURAD LTD (IL) 2023-09-06 EP disclosed
US-10294228-B2 Breathing control modulating compounds, and methods of making and using same NEURAD LTD. (IL) 2019-05-21 US disclosed
US-10294228-B2 Breathing control modulating compounds, and methods of making and using same NEURAD LTD. (IL) 2019-05-21 US disclosed
US-20180141953-A1 Novel Breathing Control Modulating Compounds, and Methods of Making and Using Same NEURAD LTD. (IL) 2018-05-24 US disclosed
US-20180141953-A1 Novel Breathing Control Modulating Compounds, and Methods of Making and Using Same NEURAD LTD. (IL) 2018-05-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180141953-A1 Novel Breathing Control Modulating Compounds, and Methods of Making and Using Same MTNR1B, CHRM3, PER2 SLC29A1 4472/4885CDK2 4026/4885CCNE1 4167/4885
US-20250057848-A1 GAL475 COMPOSITIONS AND METHODS OF USE THEREOF GPR119, GPR35, GPR55 SLC29A1 2077/4885CDK2 3942/4885CCNE1 2993/4885
US-10294228-B2 Breathing control modulating compounds, and methods of making and using same MTNR1B, PDE3A, CHRM3 SLC29A1 4518/4885CDK2 4190/4885CCNE1 4321/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.