SCHEMBL20164639

SCHEMBL20164639

CCCNc1nc(N(C)C)nc2c(N(C)CCO)ncnc12

nearest known ligand 0.53

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
SLC29A1 Q99808 11/20 0.53
MAPK1 P28482 1/20 0.41
HSD17B10 Q99714 1/20 0.37
ALDH1A1 P00352 2/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
PRUNE1 Q86TP1 1/20 0.33
ABL1 P00519 1/20 0.32
SRC P12931 1/20 0.32
CHEK1 O14757 1/20 0.32
STK4 Q13043 1/20 0.31
STK3 Q13188 1/20 0.31
LRRK2 Q5S007 1/20 0.31
KDM4E B2RXH2 1/20 0.31
KMT2A Q03164 1/20 0.31
HTT P42858 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL20164562 0.99 SLC29A1 (0.52) SLC29A1MAPK1HSD17B10ALDH1A1SMN1; SMN2
SCHEMBL20164522 0.84 SLC29A1 (0.40) SLC29A1ABL1SRC
Hydrochloric Acid SCHEMBL20164536 0.83 SLC29A1 (0.39) SLC29A1ABL1SRC
SCHEMBL20164445 0.83 SLC29A1 (0.55) SLC29A1ALDH1A1SMN1; SMN2KDM4EHTT
Hydrochloric Acid SCHEMBL20164699 0.81 SLC29A1 (0.53) SLC29A1ALDH1A1SMN1; SMN2KDM4EHTT
SCHEMBL20164527 0.81 SLC29A1 (0.52) SLC29A1ALDH1A1SMN1; SMN2STK3KDM4E
SCHEMBL20164344 0.80 SLC29A1 (0.47) SLC29A1HSD17B10ALDH1A1SMN1; SMN2ABL1
Hydrochloric Acid SCHEMBL20164424 0.80 SLC29A1 (0.51) SLC29A1ALDH1A1SMN1; SMN2STK3KDM4E
SCHEMBL20164618 0.74 SLC29A1 (0.45) SLC29A1ALDH1A1SMN1; SMN2ABL1SRC
SCHEMBL16094242 0.74 SLC29A1 (0.62) SLC29A1HSD17B10ALDH1A1SMN1; SMN2ABL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180141953-A1 Novel Breathing Control Modulating Compounds, and Methods of Making and Using Same NEURAD LTD. (IL) 2018-05-24 US claimed
US-20250057848-A1 GAL475 COMPOSITIONS AND METHODS OF USE THEREOF NEURIM PHARMACEUTICALS (1991) LTD. (IL) 2025-02-20 US disclosed
EP-3316890-B1 NOVEL BREATHING CONTROL MODULATING COMPOUNDS, AND METHODS OF MAKING AND USING SAME NEURAD LTD (IL) 2023-09-06 EP disclosed
US-10294228-B2 Breathing control modulating compounds, and methods of making and using same NEURAD LTD. (IL) 2019-05-21 US disclosed
US-20180141953-A1 Novel Breathing Control Modulating Compounds, and Methods of Making and Using Same NEURAD LTD. (IL) 2018-05-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180141953-A1 Novel Breathing Control Modulating Compounds, and Methods of Making and Using Same MTNR1B, CHRM3, PER2 SLC29A1 4472/4885MAPK1 4681/4885HSD17B10 1601/4885
US-20250057848-A1 GAL475 COMPOSITIONS AND METHODS OF USE THEREOF GPR119, GPR35, GPR55 SLC29A1 2077/4885MAPK1 3271/4885HSD17B10 153/4885
US-10294228-B2 Breathing control modulating compounds, and methods of making and using same MTNR1B, PDE3A, CHRM3 SLC29A1 4518/4885MAPK1 4702/4885HSD17B10 1514/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.