Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 9/20 | 0.44 |
| ▸ | CA1 | P00915 | 4/20 | 0.44 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.39 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | NT5E | P21589 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | CA6 | P23280 | 1/20 | 0.35 |
| ▸ | CA5A | P35218 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL775755 | 0.88 | LMNA (0.41) | CA2CA1LMNASMN1; SMN2TSHR | |
| SCHEMBL20164792 | 0.87 | CA2 (0.45) | CA2CA1PTPN2PTPN1PTPN6 | |
| SCHEMBL20560555 | 0.83 | CA2 (0.43) | CA2CA1LMNASMN1; SMN2 | |
| SCHEMBL30446884 | 0.82 | CA2 (0.57) | CA2CA1MGLLLMNASMN1; SMN2 | |
| SCHEMBL776683 | 0.81 | LMNA (0.45) | CA2CA1PTPN2PTPN1PTPN6 | |
| SCHEMBL10377765 | 0.79 | CA1 (0.41) | CA2CA1LMNASMN1; SMN2TSHR | |
| SCHEMBL778771 | 0.78 | LMNA (0.43) | CA2CA1LMNASMN1; SMN2TSHR | |
| SCHEMBL778371 | 0.78 | TSHR (0.47) | CA2CA1LMNASMN1; SMN2TSHR | |
| SCHEMBL4333544 | 0.78 | CA2 (0.49) | CA2CA1MGLLLMNASMN1; SMN2 | |
| SCHEMBL1806460 | 0.75 | CA2 (0.70) | CA2CA1MGLLLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240132432-A1 | FLUORINE-CONTAINING PILLARARENE | KYOTO UNIVERSITY (JP) | 2024-04-25 | — | — | US | disclosed |
| EP-4357330-A1 | FLUORINE-CONTAINING PILLARARENE | Kyoto University (JP) | 2024-04-24 | — | — | EP | disclosed |
| WO-2022265084-A1 | FLUORINE-CONTAINING PILLARARENE | 国立大学法人京都大学 | 2022-12-22 | — | — | WO | disclosed |
| US-8513162-B2 | Halogen-containing organosulfur compound and use thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-08-20 | — | — | US | disclosed |
| US-20110257226-A1 | HALOGEN-CONTAINING ORGANOSULFUR COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-10-20 | — | — | US | disclosed |
| EP-2376450-A1 | HALOGEN-CONTAINING ORGANOSULFUR COMPOUNDS AND USE THEREOF FOR CONTROLLING ARTHROPOD PEST | Sumitomo Chemical Company, Limited (JP) | 2011-10-19 | — | — | EP | disclosed |
| WO-2010074327-A1 | HALOGEN-CONTAINING ORGANOSULFUR COMPOUNDS AND USE THEREOF FOR CONTROLLING ARTHROPOD PEST | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-07-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240132432-A1 | FLUORINE-CONTAINING PILLARARENE | FOXK1, FXR1, AFF1 | CA2 4783/4885CA1 2415/4885PTPN2 3580/4885 |
| US-20110257226-A1 | HALOGEN-CONTAINING ORGANOSULFUR COMPOUND AND USE THEREOF | C1S, C5, L3MBTL3 | CA2 3772/4885CA1 4180/4885PTPN2 3044/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.