Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALM1 | P0DP23 | 6/20 | 0.59 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.58 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.56 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.56 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.56 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.56 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.56 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.56 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.51 |
| ▸ | NOS2 | P35228 | 1/20 | 0.51 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.43 |
| ▸ | TTR | P02766 | 1/20 | 0.43 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.43 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.43 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.43 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.43 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL402666 | 0.84 | ALDH1A1 (0.58) | CALM1AKR1B1CYP3A4CYP1A1CYP1B1 | |
| SCHEMBL29389280 | 0.81 | CALM1 (0.61) | CALM1PTGS2GABRA1GABRG2GABRB3 | |
| SCHEMBL10536298 | 0.81 | CALM1 (0.61) | CALM1PTGS2GABRA1GABRG2GABRB3 | |
| SCHEMBL1650366 | 0.81 | CALM1 (0.61) | CALM1PTGS2GABRA1GABRG2GABRB3 | |
| SCHEMBL5880258 | 0.81 | PTGS2 (0.65) | CALM1PTGS2GABRA1GABRG2GABRB3 | |
| SCHEMBL19663703 | 0.79 | CALM1 (0.59) | CALM1PTGS2GABRA1GABRG2GABRB3 | |
| SCHEMBL11941632 | 0.79 | CALM1 (0.59) | CALM1PTGS2GABRA1GABRG2GABRB3 | |
| SCHEMBL30279788 | 0.79 | CALM1 (0.59) | CALM1PTGS2GABRA1GABRG2GABRB3 | |
| SCHEMBL6827660 | 0.79 | CALM1 (0.54) | CALM1PTGS2GABRA1GABRG2GABRB3 | |
| SCHEMBL9773883 | 0.78 | PTGS2 (0.77) | CALM1PTGS2GABRA1GABRG2GABRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018090805-A1 | SKIN-PROTECTION COMPOSITION CONTAINING DENDROBIUM-BASED INGREDIENTS | HONG KONG BAPTIST UNIVERSITY (CN) | 2018-05-24 | — | — | WO | disclosed |