Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 3/20 | 0.65 |
| ▸ | CALM1 | P0DP23 | 6/20 | 0.61 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.58 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.58 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.58 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.58 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.58 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.58 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.53 |
| ▸ | NOS2 | P35228 | 1/20 | 0.53 |
| ▸ | TTR | P02766 | 1/20 | 0.48 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.48 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | ABL1 | P00519 | 1/20 | 0.45 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.45 |
| ▸ | BCR | P11274 | 1/20 | 0.45 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11258820 | 0.84 | ALDH1A1 (0.53) | PTGS2CALM1GABRA1GABRG2GABRB3 | |
| SCHEMBL88823 | 0.84 | ALDH1A1 (0.61) | PTGS2CALM1CYP1A1CYP1B1AKR1B1 | |
| SCHEMBL9773883 | 0.83 | PTGS2 (0.77) | PTGS2CALM1GABRA1GABRG2GABRB3 | |
| SCHEMBL30195497 | 0.83 | PTGS2 (0.77) | PTGS2CALM1GABRA1GABRG2GABRB3 | |
| SCHEMBL10536298 | 0.83 | CALM1 (0.61) | PTGS2CALM1GABRA1GABRG2GABRB3 | |
| SCHEMBL29389280 | 0.83 | CALM1 (0.61) | PTGS2CALM1GABRA1GABRG2GABRB3 | |
| SCHEMBL1650366 | 0.83 | CALM1 (0.61) | PTGS2CALM1GABRA1GABRG2GABRB3 | |
| SCHEMBL20165013 | 0.81 | CALM1 (0.59) | PTGS2CALM1GABRA1GABRG2GABRB3 | |
| SCHEMBL8048694 | 0.81 | LTA4H (0.48) | PTGS2CALM1GABRA1GABRG2GABRB3 | |
| SCHEMBL19663703 | 0.81 | CALM1 (0.59) | PTGS2CALM1GABRA1GABRG2GABRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119541903-B | Method for identifying effectiveness of gastrodia elata extract in preventing and treating parkinsonism | 中国农业科学院农产品加工研究所 | 2025-06-13 | — | — | CN | claimed |
| CN-119541903-A | Method for identifying effectiveness of gastrodia elata extract in preventing and treating parkinsonism | 中国农业科学院农产品加工研究所 | 2025-02-28 | — | — | CN | claimed |
| CN-119541903-B | Method for identifying effectiveness of gastrodia elata extract in preventing and treating parkinsonism | 中国农业科学院农产品加工研究所 | 2025-06-13 | — | — | CN | disclosed |
| CN-119541903-A | Method for identifying effectiveness of gastrodia elata extract in preventing and treating parkinsonism | 中国农业科学院农产品加工研究所 | 2025-02-28 | — | — | CN | disclosed |
| WO-2019028456-A1 | INHIBITORS OF MICROBIALLY INDUCED AMYLOID | AXIAL BIOTHERAPEUTICS, INC. (US) | 2019-02-07 | — | — | WO | disclosed |
| US-20180090787-A1 | SOLID ELECTROLYTE COMPOSITION, ELECTRODE SHEET FOR ALL-SOLID STATE SECONDARY BATTERY, ALL-SOLID STATE SECONDARY BATTERY, AND METHODS FOR MANUFACTURING ELECTRODE SHEET FOR ALL-SOLID STATE SECONDARY BATTERY AND ALL-SOLID STATE SECONDARY BATTERY | FUJIFILM CORPORATION (JP) | 2018-03-29 | — | — | US | disclosed |
| EP-2970224-B1 | TRIPEPTIDE EPOXY KETONE PROTEASE INHIBITORS | ONYX THERAPEUTICS INC (US) | 2017-09-06 | — | — | EP | disclosed |
| EP-2537826-B1 | Fluorination of aromatic ring systems | NUTECH VENTURES (US) | 2017-03-08 | — | — | EP | disclosed |
| EP-2168952-B1 | MORPHOLINE DERIVATIVES AS RENIN INHIBITORS | MITSUBISHI TANABE PHARMA CORP (JP) | 2017-02-15 | — | — | EP | disclosed |
| US-20160368946-A1 | TRIPEPTIDE EPOXY KETONE PROTEASE INHIBITORS | ONYX THERAPEUTICS, INC. | 2016-12-22 | — | — | US | disclosed |
| US-9434761-B2 | Tripeptide epoxy ketone protease inhibitors | ONYX THERAPEUTICS, INC. (US) | 2016-09-06 | — | — | US | disclosed |
| EP-1833816-B1 | SUBSTITUTED PIPERIDINES AS RENIN INHIBITORS | NOVARTIS AG (CH) | 2009-11-11 | — | — | EP | disclosed |
| US-7045652-B2 | From alkyl boronic esters; intermediates in the preparation of 2-amino-6-(substituted-4-phenoxy)-substituted-pyridines | PFIZER INC (US) | 2006-05-16 | — | — | US | disclosed |
| EP-1519940-A1 | SUBSTITUTED ARYL BORONIC ACIDS, THEIR PREPARATION AND THEIR PRECURSORS | Pfizer Products Inc. (US) | 2005-04-06 | — | — | EP | disclosed |
| US-20040038940-A1 | Processes for preparing substituted aryl boronic acids | PFIZER INC. | 2004-02-26 | — | — | US | disclosed |
| WO-2004005301-A1 | SUBSTITUTED ARYL BORONIC ACIDS, THEIR PREPARATION AND THEIR PRECURSORS | PFIZER PRODUCTS INC. (US) | 2004-01-15 | — | — | WO | disclosed |
| WO-2003068233-A1 | NICOTINAMIDE DERIVATIVES AND A TIOTROPIUM SALT IN COMBINATION FOR THE TREATMENT OF E.G. INFLAMMATORY, ALLERGIC AND RESPIRATORY DISEASES | PFIZER LIMITED (GB) | 2003-08-21 | — | — | WO | disclosed |
| US-5075415-A | ADHESIVE COMPOSITION FOR FIBROUS MATERIALS BASED ON PHENOL-AMINOPHENOL-FORMALDEHYDE CONDENSATION PRODUCTS | BRIDGESTONE CORPORATION (JP) | 1991-12-24 | — | — | US | disclosed |
| EP-0298704-A2 | Adhesive composition for fibrous materials and process of its preparation | Bridgestone Corporation (JP) | 1989-01-11 | — | — | EP | disclosed |
| US-4378453-A | ALKOXYPHENOL DERIVATIVE-RESORCIN DERIVATIVE-FORMALDEHYDE COCONDENSATE | BRIDGESTONE TIRE CO., LTD. (JP) | 1983-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160368946-A1 | TRIPEPTIDE EPOXY KETONE PROTEASE INHIBITORS | PREP, CTRL, ENPEP | PTGS2 485/4885CALM1 4369/4885GABRA1 3586/4885 |
| US-20040038940-A1 | Processes for preparing substituted aryl boronic acids | NOS1, NOS2, CYP1B1 | PTGS2 446/4885CALM1 2860/4885GABRA1 308/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.