Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALM1 | P0DP23 | 5/20 | 0.61 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.59 |
| ▸ | ACHE | P22303 | 1/20 | 0.58 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.58 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.58 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.58 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.58 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.58 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.58 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.53 |
| ▸ | NOS2 | P35228 | 1/20 | 0.53 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
| ▸ | TTR | P02766 | 1/20 | 0.44 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.44 |
| ▸ | DAO | P14920 | 1/20 | 0.44 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10536298 | 1.00 | CALM1 (0.61) | CALM1PTGS2ACHEGABRA1GABRG2 | |
| SCHEMBL29389280 | 1.00 | CALM1 (0.61) | CALM1PTGS2ACHEGABRA1GABRG2 | |
| SCHEMBL65276 | 0.86 | ALDH1A1 (0.58) | CALM1PTGS2ACHEAKR1B1CYP3A4 | |
| SCHEMBL1621101 | 0.86 | DAO (0.53) | CALM1PTGS2ACHEGABRA1GABRG2 | |
| SCHEMBL28123040 | 0.84 | ALDH1A1 (0.55) | CALM1PTGS2AKR1B1CYP3A4CYP1A1 | |
| SCHEMBL5880258 | 0.83 | PTGS2 (0.65) | CALM1PTGS2GABRA1GABRG2GABRB3 | |
| SCHEMBL1620230 | 0.81 | GRIN2D (0.47) | CALM1PTGS2ACHEGABRA1GABRG2 | |
| SCHEMBL30279788 | 0.81 | CALM1 (0.59) | CALM1PTGS2GABRA1GABRG2GABRB3 | |
| SCHEMBL11941632 | 0.81 | CALM1 (0.59) | CALM1PTGS2GABRA1GABRG2GABRB3 | |
| SCHEMBL19663703 | 0.81 | CALM1 (0.59) | CALM1PTGS2GABRA1GABRG2GABRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12459883-B2 | Substituted hydroxystilbene compounds and derivatives synthesis and uses thereof | Kynan Duke IP, LLC (US) | 2025-11-04 | — | — | US | disclosed |
| WO-2025001407-A1 | POLYARYL-CONTAINING MACROCYCLIC COMPOUNDS AND USES THEREOF | 浙江养生堂天然药物研究所有限公司 | 2025-01-02 | — | — | WO | disclosed |
| US-20230159421-A1 | SUBSTITUTED HYDROXYSTILBENE COMPOUNDS AND DERIVATIVES SYNTHESIS AND USES THEREOF | Kynan Duke IP, LLC (US) | 2023-05-25 | — | — | US | disclosed |
| US-20230159421-A1 | SUBSTITUTED HYDROXYSTILBENE COMPOUNDS AND DERIVATIVES SYNTHESIS AND USES THEREOF | Kynan Duke IP, LLC (US) | 2023-05-25 | — | — | US | disclosed |
| CN-115485259-A | Substituted hydroxystilbene compounds and derivatives, synthesis and use thereof | 凯楠公爵IP有限责任公司 | 2022-12-16 | — | — | CN | disclosed |
| WO-2022251191-A1 | ONE-COMPONENT DELIVERY SYSTEM FOR NUCLEIC ACIDS | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2022-12-01 | — | — | WO | disclosed |
| CN-114097780-B | Method for preparing bactericide for inhibiting botrytis cinerea and application | 吉林大学 | 2022-11-08 | — | — | CN | disclosed |
| CN-114097780-A | Method for preparing bactericide for inhibiting botrytis cinerea and application | 吉林大学 | 2022-03-01 | — | — | CN | disclosed |
| WO-2021127743-A1 | SUBSTITUTED HYDROXYSTILBENE COMPOUNDS AND DERIVATIVES SYNTHESIS AND USES THEREOF | Kynan Duke IP, LLC (US) | 2021-07-01 | — | — | WO | disclosed |
| US-10550095-B2 | Cancerous cell growth inhibiting compounds | WISYS TECHNOLOGY FOUNDATION, INC. (US) | 2020-02-04 | — | — | US | disclosed |
| US-20070292545-A1 | ANTI-INFECTIVE AGENTS AND METHODS OF USE | WISYS TECHNOLOGY FOUNDATION | 2007-12-20 | — | — | US | disclosed |
| US-20070292545-A1 | ANTI-INFECTIVE AGENTS AND METHODS OF USE | WISYS TECHNOLOGY FOUNDATION | 2007-12-20 | — | — | US | disclosed |
| US-20070010511-A1 | Organic compounds | NOVARTIS PHARMA AG (CH) | 2007-01-11 | — | — | US | disclosed |
| EP-1670760-A1 | ORGANIC COMPOUNDS | Speedel Experimenta AG (CH) | 2006-06-21 | — | — | EP | disclosed |
| WO-2005061457-A1 | ORGANIC COMPOUNDS | SPEEDEL EXPERIMENTA AG (CH) | 2005-07-07 | — | — | WO | disclosed |
| US-6635655-B1 | Agonists or antagonists of peroxisome proliferator-activated receptors | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2003-10-21 | — | — | US | disclosed |
| US-6376512-B1 | FOR TREATING PHYSIOLOGICAL CONDITION IN PATIENT WHEREIN SAID CONDITION IS ASSOCIATED WITH A PHYSIOLOGICALLY DETRIMENTAL LEVELS OF INSULIN, GLUCOSE, FREE FATTY ACIDS, OR TRIGLYCERIDES | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2002-04-23 | — | — | US | disclosed |
| US-5059610-A | QUINOLINE DERIVATIVES AND THEIR USE AS ANTAGONISTS OF LEUKOTRIENE D4 | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1991-10-22 | — | — | US | disclosed |
| US-4920132-A | Quinoline derivatives and use thereof as antagonists of leukotriene D4 | RORER PHARMACEUTICAL CORP. (US) | 1990-04-24 | — | — | US | disclosed |
| US-4306083-A | Multiphase oxidation of alcohol to aldehyde | THE DOW CHEMICAL COMPANY (US) | 1981-12-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070010511-A1 | Organic compounds | REN, ACE, ACE2 | CALM1 2312/4885PTGS2 279/4885ACHE 403/4885 |
| US-10550095-B2 | Cancerous cell growth inhibiting compounds | TYR, MKI67, MC1R | CALM1 661/4885PTGS2 284/4885ACHE 3485/4885 |
| US-20070292545-A1 | ANTI-INFECTIVE AGENTS AND METHODS OF USE | H1-3, H1-0, H1-2 | CALM1 2730/4885PTGS2 1061/4885ACHE 150/4885 |
| US-12459883-B2 | Substituted hydroxystilbene compounds and derivatives synthesis and uses thereof | CYP8B1, HSD11B1, HSD11B2 | CALM1 3582/4885PTGS2 213/4885ACHE 3406/4885 |
| US-20230159421-A1 | SUBSTITUTED HYDROXYSTILBENE COMPOUNDS AND DERIVATIVES SYNTHESIS AND USES THEREOF | CYP8B1, HSD11B1, HSD11B2 | CALM1 3582/4885PTGS2 213/4885ACHE 3406/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.