Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 5/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4967941 | 0.97 | — | — | |
| SCHEMBL2639323 | 0.86 | MEN1 (0.38) | MEN1KMT2ATSHRMAPK1 | |
| SCHEMBL43474 | 0.86 | MEN1 (0.38) | MEN1KMT2ATSHRMAPK1 | |
| SCHEMBL202447 | 0.86 | MEN1 (0.38) | MEN1KMT2ATSHRMAPK1 | |
| SCHEMBL454356 | 0.86 | MEN1 (0.38) | MEN1KMT2ATSHRMAPK1 | |
| SCHEMBL23765660 | 0.86 | MEN1 (0.38) | MEN1KMT2ATSHRMAPK1 | |
| SCHEMBL19107454 | 0.86 | MEN1 (0.38) | MEN1KMT2ATSHRMAPK1 | |
| SCHEMBL14745208 | 0.86 | MEN1 (0.38) | MEN1KMT2ATSHRMAPK1 | |
| SCHEMBL12775011 | 0.86 | MEN1 (0.38) | MEN1KMT2ATSHRMAPK1 | |
| SCHEMBL19107453 | 0.86 | MEN1 (0.38) | MEN1KMT2ATSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12570606-B2 | Myeloperoxidase imaging agents | THE GENERAL HOSPITAL CORPORATION (US) | 2026-03-10 | — | — | US | disclosed |
| US-20240336642-A1 | INHIBITORS OF 12/15-LIPOXYGENASE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2024-10-10 | — | — | US | disclosed |
| EP-4384161-A1 | INHIBITORS OF 12/15-LIPOXYGENASE | The General Hospital Corporation (US) | 2024-06-19 | — | — | EP | disclosed |
| EP-3541431-B1 | MYELOPEROXIDASE IMAGING AGENTS | MASSACHUSETTS GEN HOSPITAL (US) | 2024-04-17 | — | — | EP | disclosed |
| WO-2023019090-A1 | INHIBITORS OF 12/15-LIPOXYGENASE | THE GENERAL HOSPITAL CORPORATION (US) | 2023-02-16 | — | — | WO | disclosed |
| WO-2023019090-A1 | INHIBITORS OF 12/15-LIPOXYGENASE | THE GENERAL HOSPITAL CORPORATION (US) | 2023-02-16 | — | — | WO | disclosed |
| CN-110177581-B | Myeloperoxidase imaging agents | 通用医疗公司 | 2023-01-03 | — | — | CN | disclosed |
| CN-113045477-B | Preparation method of fluorine-containing primary amine intermediate | 中蓝晨光化工研究设计院有限公司 | 2022-11-01 | — | — | CN | disclosed |
| US-20220340524-A1 | Myeloperoxidase Imaging Agents | THE GENERAL HOSPITAL CORPORATION | 2022-10-27 | — | — | US | disclosed |
| US-11352326-B2 | Myeloperoxidase imaging agents | THE GENERAL HOSPITAL CORPORATION (US) | 2022-06-07 | — | — | US | disclosed |
| US-11352326-B2 | Myeloperoxidase imaging agents | THE GENERAL HOSPITAL CORPORATION (US) | 2022-06-07 | — | — | US | disclosed |
| CN-113045477-A | Preparation method of fluorine-containing primary amine intermediate | 中蓝晨光化工研究设计院有限公司 | 2021-06-29 | — | — | CN | disclosed |
| US-20200407360-A1 | Process for Producing Fluorinated Compounds Using Alcohol Solvent Having Unsaturated Hydrocarbon | FUTURECHEM CO., LTD (KR) | 2020-12-31 | — | — | US | disclosed |
| US-20190315689-A1 | Myeloperoxidase Imaging Agents | THE GENERAL HOSPITAL CORPORATION | 2019-10-17 | — | — | US | disclosed |
| US-20190315689-A1 | Myeloperoxidase Imaging Agents | THE GENERAL HOSPITAL CORPORATION | 2019-10-17 | — | — | US | disclosed |
| EP-3541431-A1 | MYELOPEROXIDASE IMAGING AGENTS | The General Hospital Corporation (US) | 2019-09-25 | — | — | EP | disclosed |
| US-10196412-B2 | Probe for imaging PARP-1 activity | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2019-02-05 | — | — | US | disclosed |
| WO-2018094005-A1 | MYELOPEROXIDASE IMAGING AGENTS | THE GENERAL HOSPITAL CORPORATION (US) | 2018-05-24 | — | — | WO | disclosed |
| WO-2018094005-A1 | MYELOPEROXIDASE IMAGING AGENTS | THE GENERAL HOSPITAL CORPORATION (US) | 2018-05-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240336642-A1 | INHIBITORS OF 12/15-LIPOXYGENASE | ALOX15, LOX, ALOX12 | MEN1 4622/4885KMT2A 3334/4885APP 2089/4885 |
| US-20200407360-A1 | Process for Producing Fluorinated Compounds Using Alcohol Solvent Having Unsaturated Hydrocarbon | FASN, CYP2F1, FDFT1 | MEN1 689/4885KMT2A 3159/4885APP 2205/4885 |
| US-10196412-B2 | Probe for imaging PARP-1 activity | PARP1, PARP2, PARP12 | MEN1 1302/4885KMT2A 687/4885APP 3582/4885 |
| US-20220340524-A1 | Myeloperoxidase Imaging Agents | MPO, CAT, EPX | MEN1 3263/4885KMT2A 1685/4885APP 4825/4885 |
| US-12570606-B2 | Myeloperoxidase imaging agents | MPO, CBR1, NOX1 | MEN1 3759/4885KMT2A 3400/4885APP 4753/4885 |
| US-20190315689-A1 | Myeloperoxidase Imaging Agents | MPO, CAT, EPX | MEN1 2886/4885KMT2A 3281/4885APP 4450/4885 |
| US-11352326-B2 | Myeloperoxidase imaging agents | MPO, CAT, EPX | MEN1 2886/4885KMT2A 3281/4885APP 4450/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.