Sugi Predict

Sugi Predict / Compounds / 1-Naphthol

1-Naphthol

1-Naphthol

SCHEMBL2016852

COC.COc1ccc2ccccc2c1.Oc1cccc2ccccc12

nearest known ligand 0.63

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CYP1A2 P05177 4/20 0.63
▸ CYP2A6 P11509 1/20 0.63
▸ ABCG2 Q9UNQ0 3/20 0.50
▸ KMT2A Q03164 5/20 0.49
▸ MEN1 O00255 4/20 0.49
▸ NPC1 O15118 2/20 0.49
▸ RAB9A P51151 2/20 0.49
▸ L3MBTL1 Q9Y468 1/20 0.49
▸ ALDH1A1 P00352 2/20 0.47
▸ LMNA P02545 1/20 0.47
▸ GAA P10253 1/20 0.47
▸ MAPT P10636 1/20 0.47
▸ TDP1 Q9NUW8 1/20 0.47
▸ ALOX12 P18054 1/20 0.47
▸ HIF1A Q16665 1/20 0.47
▸ PHLPP2 Q6ZVD8 1/20 0.47
▸ HSD17B10 Q99714 1/20 0.47
▸ MTNR1A P48039 1/20 0.47
▸ MAOB P27338 1/20 0.46
▸ RRM1 P23921 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
1-Naphthol SCHEMBL7584597 0.90 CYP1A2 (0.55) CYP1A2CYP2A6ABCG2KMT2AMEN1
SCHEMBL28628067 0.88 CYP1A2 (0.70) CYP1A2CYP2A6ABCG2KMT2AMEN1
SCHEMBL30277953 0.86 CYP1A2 (0.55) CYP1A2CYP2A6KMT2AMEN1NPC1
SCHEMBL774076 0.86 CYP1A2 (0.55) CYP1A2CYP2A6KMT2AMEN1NPC1
SCHEMBL169434 0.86 MTNR1A (0.55) CYP1A2CYP2A6MTNR1A
1-Naphthol SCHEMBL558316 0.84 CYP1A2 (0.81) CYP1A2CYP2A6KMT2AALDH1A1GAA
1-Naphthol SCHEMBL28030286 0.83 HDAC4 (0.61) CYP1A2CYP2A6ABCG2KMT2AMEN1
Naphthalene SCHEMBL18344242 0.82 CYP1A2 (0.95) CYP1A2CYP2A6KMT2AMEN1NPC1
Methyl Alcohol SCHEMBL5664821 0.80 CYP1A2 (0.91) CYP1A2CYP2A6KMT2AMEN1NPC1
SCHEMBL29353188 0.80 CYP1A2 (1.00) CYP1A2CYP2A6KMT2AMEN1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3596195-A1 BENEFIT AGENT CONTAINING DELIVERY PARTICLE The Procter and Gamble Company (US) 2020-01-22 — — EP disclosed
EP-3596192-A1 BENEFIT AGENT CONTAINING DELIVERY PARTICLE SLURRIES The Procter and Gamble Company (US) 2020-01-22 — — EP disclosed
WO-2018169532-A1 BENEFIT AGENT CONTAINING DELIVERY PARTICLE THE PROCTER & GAMBLE COMPANY (US) 2018-09-20 — — WO disclosed
WO-2018169531-A1 BENEFIT AGENT CONTAINING DELIVERY PARTICLE SLURRIES THE PROCTER & GAMBLE COMPANY (US) 2018-09-20 — — WO disclosed
WO-2017158497-A1 HYDROPHOBICALLY MODIFIED UREA ETHERS AS STRUCTURANTS FOR HYDROPHOBIC SYSTEMS PROCTER & GAMBLE INERNATIONAL OPERATIONS SA (CH) 2017-09-21 — — WO disclosed
EP-2741731-A1 ENCAPSULATES The Procter and Gamble Company (US) 2014-06-18 — — EP disclosed
WO-2013022949-A1 ENCAPSULATES THE PROCTER & GAMBLE COMPANY (US) 2013-02-14 — — WO disclosed
EP-2513280-A1 COMPOSITION COMPRISING ENCAPSULATES, AND PROCESS FOR MAKING THEM The Procter & Gamble Company (US) 2012-10-24 — — EP disclosed
EP-2512406-A1 PERFUMES AND PERFUME ENCAPSULATES The Procter & Gamble Company (US) 2012-10-24 — — EP disclosed
WO-2012085864-A1 ENCAPSULATES PROCTER & GAMBLE INTERNATIONAL OPERATIONS SA (CH) 2012-06-28 — — WO disclosed
WO-2011075551-A1 PERFUMES AND PERFUME ENCAPSULATES THE PROCTER & GAMBLE COMPANY (US) 2011-06-23 — — WO disclosed
WO-2011075556-A1 COMPOSITION COMPRISING ENCAPSULATES, AND PROCESS FOR MAKING THEM THE PROCTER & GAMBLE COMPANY (US) 2011-06-23 — — WO disclosed