SCHEMBL2016961

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2015259	0.90	HTR6 (0.45)	KMT2ABRD4SMN1; SMN2LMNAHTR6
	SCHEMBL2017184	0.86	BRD4 (0.45)	PKMGHSRBRD4ALDH1A1SMN1; SMN2
	SCHEMBL2017386	0.86	HTR2C (0.47)	PKMKMT2AMAPTPKLRSMN1; SMN2
	SCHEMBL2015014	0.86	SMN1; SMN2 (0.52)	PKMKMT2AGHSRBRD4ALDH1A1
	SCHEMBL2014308	0.85	HTR6 (0.49)	PKMKMT2ASMN1; SMN2LMNAHTR6
	SCHEMBL2017668	0.85	BRD4 (0.48)	PKMKMT2ABRD4MEN1NLRP3
	SCHEMBL692281	0.85	HTR6 (0.49)	PKMKMT2AMEN1ALDH1A1MAPT
	SCHEMBL2014452	0.85	MAPT (0.45)	PKMKMT2ABRD4ALDH1A1MAPT
	SCHEMBL2018282	0.85	HTR2C (0.51)	PKMKMT2ABRD4ALDH1A1LMNA
	SCHEMBL2014809	0.85	HTR6 (0.47)	GHSRBRD4ALDH1A1PKLRHTR6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.