SCHEMBL692281

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2015962	0.92	HTR2C (0.41)	HTR6HTR2CPKMHTR2AHTR2B
	SCHEMBL2017184	0.90	BRD4 (0.45)	HTR6HTR2CPKMHTR2AHTR2B
	SCHEMBL2015259	0.90	HTR6 (0.45)	HTR6HTR2CHTR2AHTR2BKMT2A
	SCHEMBL2014308	0.89	HTR6 (0.49)	HTR6HTR2CPKMHTR2BKMT2A
	SCHEMBL2014452	0.89	MAPT (0.45)	HTR6HTR2CPKMTP53HTR2A
	SCHEMBL2018282	0.89	HTR2C (0.51)	HTR6HTR2CPKMHTR2AHTR2B
	SCHEMBL2017384	0.88	HTR6 (0.47)	HTR6HTR2CHTR2AHTR2BMAPT
	SCHEMBL2014922	0.85	MEN1 (0.44)	HTR6HTR2CPKMTP53HTR2A
	SCHEMBL2016961	0.85	PKM (0.52)	HTR6HTR2CPKMHTR2AMAPT
	SCHEMBL2015136	0.85	DDB1 (0.49)	HTR6HTR2CMAPTHDAC1HDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.