Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | FKBP1A | P62942 | 4/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16870518 | 0.82 | HSD17B10 (0.41) | HSD17B10KMT2AOPRM1OPRL1 | |
| SCHEMBL7628433 | 0.79 | OPRM1 (0.49) | LMNAFKBP1AOPRM1OPRL1OPRD1 | |
| SCHEMBL23052290 | 0.78 | LMNA (0.46) | LMNAKMT2AFKBP1AOPRM1OPRL1 | |
| SCHEMBL13853687 | 0.76 | ALDH1A1 (0.52) | HSD17B10LMNAKMT2AUSP2SMN1; SMN2 | |
| SCHEMBL24629816 | 0.74 | HSD17B10 (0.44) | HSD17B10KMT2A | |
| SCHEMBL14970350 | 0.72 | OPRM1 (0.50) | FKBP1AOPRM1OPRL1 | |
| SCHEMBL14451257 | 0.72 | EPHX1 (0.50) | HSD17B10KMT2AFKBP1ASMN1; SMN2MEN1 | |
| SCHEMBL8684584 | 0.71 | ALDH1A1 (0.42) | LMNAKMT2AUSP2CYP3A4SMN1; SMN2 | |
| SCHEMBL19722914 | 0.71 | OPRM1 (0.35) | FKBP1AOPRM1OPRL1 | |
| SCHEMBL20289519 | 0.71 | SLC6A4 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2772480-B2 | HIV REPLICATION INHIBITOR | SHIONOGI & CO (JP) | 2020-12-09 | — | — | EP | disclosed |
| EP-2772480-B1 | HIV REPLICATION INHIBITOR | SHIONOGI & CO (JP) | 2018-05-23 | — | — | EP | disclosed |