Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 5/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.36 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 3/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15869712 | 0.82 | LMNA (0.45) | LMNAMEN1KMT2A | |
| SCHEMBL7628433 | 0.81 | OPRM1 (0.49) | LMNAMTNR1AMTNR1BFKBP1AOPRM1 | |
| SCHEMBL19151155 | 0.79 | LMNA (0.42) | LMNAMEN1KMT2AMTNR1AMTNR1B | |
| SCHEMBL20171068 | 0.78 | HSD17B10 (0.46) | LMNAMEN1KMT2AFKBP1AOPRM1 | |
| SCHEMBL3248152 | 0.76 | TSHR (0.37) | LMNAKMT2AFKBP1ACYP2C19 | |
| SCHEMBL21766643 | 0.76 | P2RX7 (0.41) | LMNAMEN1KMT2AMTNR1AMTNR1B | |
| SCHEMBL18869250 | 0.76 | ALDH1A1 (0.50) | LMNAKMT2ACYP2C19 | |
| SCHEMBL15427281 | 0.75 | MEN1 (0.41) | LMNAMEN1KMT2AMTNR1AMTNR1B | |
| SCHEMBL21234808 | 0.75 | LMNA (0.33) | LMNA | |
| SCHEMBL14970350 | 0.74 | OPRM1 (0.50) | MTNR1AMTNR1BFKBP1AOPRM1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021038426-A1 | SUBSTITUTED 1,3-PHENYL HETEROARYL DERIVATIVES AND THEIR USE IN THE TREATMENT OF DISEASE | NOVARTIS AG (CH) | 2021-03-04 | — | — | WO | disclosed |