SCHEMBL20172764

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL25637800	0.86	MAPT (0.42)	CYP1A2CYP2C19NPC1RAB9AALOX5
	SCHEMBL17737631	0.86	NPC1 (0.39)	CYP1A2CYP2C19NPC1CYP2C9RAB9A
	SCHEMBL15747049	0.82	TOP2A (0.44)	CYP2C19NPC1RAB9AALOX5HTT
	SCHEMBL17737629	0.82	ALOX5 (0.38)	CYP1A2CYP2C19NPC1CYP2C9RAB9A
	SCHEMBL17933247	0.81	C5AR1 (0.38)	CYP2C19NPC1RAB9AALOX5HTT
	SCHEMBL24471774	0.81	ALOX5 (0.41)	CYP1A2CYP2C19NPC1CYP2C9RAB9A
	SCHEMBL18540441	0.81	NPC1 (0.36)	CYP1A2CYP2C19NPC1CYP2C9RAB9A
	SCHEMBL20172763	0.81	SIGMAR1 (0.45)	CYP1A2CYP2C19NPC1RAB9AALOX5
	SCHEMBL18627678	0.81	TNKS (0.41)	CYP2C19CYP2C9ALOX5TNKSAHR
	SCHEMBL20172767	0.81	ALOX5 (0.39)	CYP1A2NPC1RAB9AALOX5HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.