SCHEMBL2017462

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2019111	0.80	HTR2C (0.58)	HTR2AHTR2CHTR2B
	SCHEMBL692320	0.77	DRD2 (0.41)	HTR2AHTR2CHTR2BPOLBDRD2
	SCHEMBL5917470	0.75	POLB (0.49)	HTR2AHTR2CHTR2BPOLBDRD2
	SCHEMBL692247	0.73	HTR2C (0.45)	HTR2AHTR2CHTR2BPOLBDRD2
	SCHEMBL2558862	0.73	HTR2C (0.45)	HTR2AHTR2CHTR2BPOLBDRD2
	SCHEMBL11821046	0.68	HTR2C (0.55)	HTR2AHTR2CHTR2BPOLBDRD2
	SCHEMBL11829920	0.68	HTR2C (0.47)	HTR2AHTR2CHTR2BPOLBDRD2
	SCHEMBL2574804	0.67	POLB (0.35)	HTR2AHTR2CHTR2BPOLBDRD2
	SCHEMBL13684973	0.67	NOTUM (0.40)	HTR2APOLBDRD2ADRA1BHTR1A
	SCHEMBL691843	0.66	HTR2C (0.62)	HTR2AHTR2CHTR2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.