Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | GPR3 | P46089 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17533936 | 0.85 | GPR3 (0.40) | L3MBTL1GPR3ALOX5HSP90AA1 | |
| SCHEMBL20174699 | 0.82 | PDK2 (0.42) | PDK2L3MBTL1GPR3 | |
| SCHEMBL19760329 | 0.82 | PDK2 (0.38) | PDK2GPR3PTPN1ALOX5 | |
| SCHEMBL19760326 | 0.81 | PDK2 (0.40) | PDK2GPR3PTPN1ALOX5 | |
| SCHEMBL17716718 | 0.80 | DHFR (0.30) | — | |
| SCHEMBL17716690 | 0.80 | L3MBTL1 (0.35) | L3MBTL1ALOX5HSP90AA1 | |
| SCHEMBL18582210 | 0.80 | PDK2 (0.40) | PDK2L3MBTL1GPR3ALOX5 | |
| SCHEMBL19760331 | 0.79 | PDK2 (0.38) | PDK2GPR3PTPN1 | |
| SCHEMBL16855607 | 0.78 | MEN1 (0.40) | PDK2GPR3PTPN1 | |
| SCHEMBL17367237 | 0.78 | GPR3 (0.36) | L3MBTL1GPR3ALOX5HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180148639-A1 | SPIRO COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME | LG CHEM, LTD. (KR) | 2018-05-31 | — | — | US | disclosed |
| US-20180141933-A1 | SPIRO COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME | LG CHEM, LTD. (KR) | 2018-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180141933-A1 | SPIRO COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME | CRY1, NR2E3, ERG | PDK2 651/4885L3MBTL1 2838/4885GPR3 2192/4885 |
| US-20180148639-A1 | SPIRO COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME | CRY1, NR2E3, ERG | PDK2 651/4885L3MBTL1 2838/4885GPR3 2192/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.