Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR3 | P46089 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | F9 | P00740 | 1/20 | 0.30 |
| ▸ | PDE4A | P27815 | 1/20 | 0.30 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17367237 | 0.88 | GPR3 (0.36) | GPR3ALOX5MAPTMEN1KMT2A | |
| SCHEMBL18582210 | 0.87 | PDK2 (0.40) | GPR3ALOX5L3MBTL1 | |
| SCHEMBL20174701 | 0.85 | PDK2 (0.41) | GPR3ALOX5L3MBTL1HSP90AA1 | |
| SCHEMBL20199172 | 0.83 | KDM4E (0.31) | ALOX5MAPTKDM4EL3MBTL1ALDH1A1 | |
| SCHEMBL18582994 | 0.83 | L3MBTL1 (0.36) | ALOX5MEN1KMT2AL3MBTL1HSP90AA1 | |
| SCHEMBL20174805 | 0.83 | PDK2 (0.33) | ALOX5 | |
| SCHEMBL20199122 | 0.83 | PDK2 (0.33) | ALOX5 | |
| SCHEMBL17716718 | 0.82 | DHFR (0.30) | — | |
| SCHEMBL17716690 | 0.82 | L3MBTL1 (0.35) | ALOX5MEN1KMT2AL3MBTL1HSP90AA1 | |
| SCHEMBL18590012 | 0.82 | PDK2 (0.36) | ALOX5MEN1KMT2AL3MBTL1HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11075342-B2 | Spiro-type compound and organic light emitting diode comprising same | LG CHEM, LTD. | 2021-07-27 | — | — | US | disclosed |
| US-20180145261-A1 | SPIRO-TYPE COMPOUND AND ORGANIC LIGHT EMITTING DIODE COMPRISING SAME | LG CHEM, LTD. (KR) | 2018-05-24 | — | — | US | disclosed |
| US-20180145261-A1 | SPIRO-TYPE COMPOUND AND ORGANIC LIGHT EMITTING DIODE COMPRISING SAME | LG CHEM, LTD. (KR) | 2018-05-24 | — | — | US | disclosed |
| WO-2016023458-A1 | NOVEL CARBO- AND HETEROCYCLIC SPIRO COMPOUNDS AS DONOR MATERIALS FOR ORGANIC PHOTOVOLTAICS AND THEIR PREPARATION | THE UNIVERSITY OF HONG KONG (CN) | 2016-02-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11075342-B2 | Spiro-type compound and organic light emitting diode comprising same | CRY1, NR2E3, ALDH1A2 | GPR3 2438/4885ALOX5 2347/4885MAPT 821/4885 |
| US-20180145261-A1 | SPIRO-TYPE COMPOUND AND ORGANIC LIGHT EMITTING DIODE COMPRISING SAME | CRY1, NR2E3, ALDH1A2 | GPR3 2438/4885ALOX5 2347/4885MAPT 821/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.