Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | NOS3 | P29474 | 4/20 | 0.39 |
| ▸ | NOS1 | P29475 | 4/20 | 0.39 |
| ▸ | NOS2 | P35228 | 3/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | RAD52 | P43351 | 2/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5517360 | 0.91 | AR (0.44) | RENHTR1ASLC6A4NOS3NOS1 | |
| SCHEMBL17525511 | 0.86 | NOS3 (0.39) | RENHTR1ASLC6A4NOS3NOS1 | |
| SCHEMBL5516550 | 0.85 | NR3C1 (0.41) | NOS3NOS1NOS2ARMAPT | |
| SCHEMBL17859629 | 0.85 | HTR1A (0.37) | RENHTR1ASLC6A4NOS3NOS1 | |
| SCHEMBL17525514 | 0.85 | REN (0.52) | RENHTR1ASLC6A4NOS3NOS1 | |
| SCHEMBL17525515 | 0.85 | NOS3 (0.47) | RENHTR1ASLC6A4NOS3NOS1 | |
| SCHEMBL17525479 | 0.84 | NOS3 (0.38) | RENHTR1ASLC6A4NOS3NOS1 | |
| SCHEMBL282767 | 0.84 | HTR1A (0.49) | RENHTR1ASLC6A4NOS3NOS1 | |
| SCHEMBL17525510 | 0.83 | NOS3 (0.47) | RENHTR1ASLC6A4NOS3NOS1 | |
| SCHEMBL17525480 | 0.83 | NOS3 (0.38) | RENHTR1ASLC6A4NOS3NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180141922-A1 | BENZOXAZINE DERIVATIVES AND USE IN HAIR DYEING | L'OREAL (FR) | 2018-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180141922-A1 | BENZOXAZINE DERIVATIVES AND USE IN HAIR DYEING | XDH, KRT18, CYC1 | REN 317/4885HTR1A 802/4885SLC6A4 2280/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.