Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 2/20 | 0.48 |
| ▸ | KDM1A | O60341 | 2/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | JAK1 | P23458 | 1/20 | 0.36 |
| ▸ | TYK2 | P29597 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 4/20 | 0.36 |
| ▸ | DPP7 | Q9UHL4 | 4/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20177491 | 0.89 | CCKBR (0.47) | CCKBRCTSLCTSBCTSK | |
| SCHEMBL20177635 | 0.86 | KDM1A (0.41) | CCKBRKDM1ACTSLCTSBCTSK | |
| SCHEMBL20177518 | 0.77 | CCKBR (0.41) | CCKBRCTSLCTSBCTSKALDH1A1 | |
| SCHEMBL20177567 | 0.76 | FPR2 (0.52) | CTSL | |
| SCHEMBL20177674 | 0.76 | KDM1A (0.42) | CCKBRKDM1ACTSLALDH1A1GAA | |
| SCHEMBL18270477 | 0.75 | FPR2 (0.45) | CCKBR | |
| SCHEMBL20177919 | 0.75 | KDM1A (0.41) | CCKBRKDM1ACTSLALDH1A1GAA | |
| SCHEMBL22068860 | 0.73 | CA1 (0.44) | CCKBRCTSLCTSBCTSK | |
| SCHEMBL20177845 | 0.73 | BRD4 (0.47) | CTSLCTSBCTSK | |
| SCHEMBL20177499 | 0.73 | SMN1; SMN2 (0.37) | ALDH1A1GAAKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018092916-A1 | NITROGEN-CONTAINING POLYCYCLIC HETEROCYCLIC DERIVATIVE | 宇部興産株式会社 | 2018-05-24 | — | — | WO | disclosed |