Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARA | P10276 | 7/20 | 0.48 |
| ▸ | RARB | P10826 | 6/20 | 0.48 |
| ▸ | RARG | P13631 | 6/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.45 |
| ▸ | EPAS1 | Q99814 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2709569 | 0.81 | HIF1A (0.46) | RARARARBRARGHIF1AEPAS1 | |
| SCHEMBL6378001 | 0.78 | RARA (0.65) | RARARARBRARGHIF1AEPAS1 | |
| SCHEMBL422261 | 0.75 | NPC1 (0.56) | RARARARBRARGHIF1AEPAS1 | |
| SCHEMBL2708795 | 0.75 | HIF1A (0.49) | HIF1AEPAS1MEN1KMT2AALDH1A1 | |
| SCHEMBL2707051 | 0.75 | SERPINE1 (0.47) | RARARARBRARGHIF1AEPAS1 | |
| SCHEMBL2707858 | 0.75 | SERPINE1 (0.47) | RARARARBRARGHIF1AEPAS1 | |
| SCHEMBL6770754 | 0.74 | ALDH1A1 (0.46) | HIF1AEPAS1MEN1KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL2710121 | 0.74 | NPC1 (0.54) | RARARARBRARGHIF1AEPAS1 | |
| SCHEMBL25720237 | 0.73 | MEN1 (0.45) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL8616987 | 0.72 | RARA (0.65) | RARARARBRARGMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10980778-B2 | Methods for treating multiple osteochondroma (MO) | Clementia Pharmaceuticals Inc. (CA) | 2021-04-20 | — | — | US | disclosed |
| US-20190275005-A1 | METHODS FOR TREATING MULTIPLE OSTEOCHONDROMA (MO) | Clementia Pharmaceuticals Inc. (CA) | 2019-09-12 | — | — | US | disclosed |
| WO-2018090137-A1 | METHODS FOR TREATING MULTIPLE OSTEOCHONDROMA (MO) | Clementia Pharmaceuticals Inc. (CA) | 2018-05-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10980778-B2 | Methods for treating multiple osteochondroma (MO) | UTRN, VHL, SOST | RARA 1990/4885RARB 1620/4885RARG 1720/4885 |
| US-20190275005-A1 | METHODS FOR TREATING MULTIPLE OSTEOCHONDROMA (MO) | UTRN, VHL, SOST | RARA 1990/4885RARB 1620/4885RARG 1720/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.