SCHEMBL25720237

SCHEMBL25720237

N#Cc1cc(O)cc(C23CC4CC(CC(C4)C2)C3)c1

nearest known ligand 0.45

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.45
KMT2A Q03164 2/20 0.45
POLB P06746 1/20 0.45
GAA P10253 1/20 0.45
GFER P55789 1/20 0.45
PGR P06401 10/20 0.41
STS P08842 1/20 0.38
ALDH1A1 P00352 2/20 0.37
LMNA P02545 1/20 0.37
HSD11B1 P28845 1/20 0.35
CNR2 P34972 2/20 0.35
EPHX2 P34913 1/20 0.35
KDM4E B2RXH2 1/20 0.35
HPGD P15428 1/20 0.35
HSD17B10 Q99714 1/20 0.35
RAB9A P51151 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11642014 0.82 MEN1 (0.57) MEN1KMT2APOLBGAAGFER
SCHEMBL548788 0.82 MEN1 (0.57) MEN1KMT2APOLBGAAGFER
SCHEMBL25708831 0.76 PGR (0.38) MEN1KMT2APOLBGAAGFER
SCHEMBL20178896 0.73 RARA (0.48) MEN1KMT2APOLBGAAGFER
SCHEMBL4752577 0.73 PGR (0.68) MEN1KMT2APOLBGAAGFER
SCHEMBL25708866 0.70 HTT (0.48) MEN1KMT2APGRALDH1A1LMNA
SCHEMBL6698243 0.69 LMNA (0.47) MEN1KMT2APOLBGAAGFER
SCHEMBL16122423 0.69 ALDH1A1 (0.43) MEN1KMT2APOLBGAAGFER
SCHEMBL9264989 0.69 CA12 (0.52) MEN1KMT2A
SCHEMBL214163 0.69 CA12 (0.52) MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11746093-B2 Nitrogen-containing compound, electronic element, and electronic device SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2023-09-05 US disclosed
US-20230192627-A1 NITROGEN-CONTAINING COMPOUND, ELECTRONIC ELEMENT, AND ELECTRONIC DEVICE SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2023-06-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11746093-B2 Nitrogen-containing compound, electronic element, and electronic device SLC43A1, SLC7A5, L1CAM MEN1 625/4885KMT2A 2194/4885POLB 2903/4885
US-20230192627-A1 NITROGEN-CONTAINING COMPOUND, ELECTRONIC ELEMENT, AND ELECTRONIC DEVICE SLC43A1, SLC7A5, L1CAM MEN1 625/4885KMT2A 2194/4885POLB 2903/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.