Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.40 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.36 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.36 |
| ▸ | DGAT2 | Q96PD7 | 6/20 | 0.36 |
| ▸ | GRM5 | P41594 | 2/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PLK4 | O00444 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.32 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2015154 | 0.81 | TAAR1 (0.41) | SLC22A12CSNK2A2CSNK2BDGAT2CYP17A1 | |
| SCHEMBL2014653 | 0.81 | CSNK2A2 (0.39) | SLC22A12CSNK2A2CSNK2BDGAT2GRM5 | |
| SCHEMBL2017931 | 0.77 | SLC22A12 (0.41) | SLC22A12CSNK2A2CSNK2BDGAT2GRM5 | |
| SCHEMBL2018305 | 0.70 | SCN9A (0.36) | SCN9ANR1H2NR1H3 | |
| SCHEMBL2014651 | 0.70 | PIK3CD (0.39) | SLC22A12CSNK2A2CSNK2BDGAT2GRM5 | |
| SCHEMBL2015153 | 0.70 | BCL2 (0.41) | SLC22A12CSNK2A2CSNK2BDGAT2GRM5 | |
| SCHEMBL4832310 | 0.68 | LOXL2 (0.46) | PTGS2PTGS1 | |
| SCHEMBL15621376 | 0.68 | PIK3CD (0.38) | SLC22A12CSNK2A2CSNK2BDGAT2GRM5 | |
| SCHEMBL12470054 | 0.68 | PIK3CD (0.38) | SLC22A12CSNK2A2CSNK2BDGAT2GRM5 | |
| SCHEMBL2012666 | 0.66 | TAAR1 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011075630-A1 | SUBSTITUTED FUSED ARYL AND HETEROARYL DERIVATIVES AS PI3K INHIBITORS | INCYTE CORPORATION (US) | 2011-06-23 | — | — | WO | disclosed |