Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB4A | P04350 | 2/20 | 0.47 |
| ▸ | TUBB | P07437 | 2/20 | 0.47 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.47 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.47 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.47 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.47 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.47 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.47 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.47 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.47 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.47 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.47 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.47 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.47 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | DHFR | P00374 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4238248 | 0.81 | PTGS2 (0.52) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL8910416 | 0.80 | PTGS2 (0.70) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL26466869 | 0.78 | CYP11B1 (0.51) | CYP3A4CYP11B1CYP11B2 | |
| SCHEMBL13813583 | 0.74 | ACHE (0.52) | ACHEALDH1A1TSHRHSD17B10GAA | |
| SCHEMBL13559004 | 0.72 | CYP11B1 (0.45) | CYP3A4CYP11B1CYP11B2 | |
| SCHEMBL10978459 | 0.71 | DHFR (0.66) | CYP3A4DHFRMEN1SLC22A1ALDH1A1 | |
| SCHEMBL21251416 | 0.71 | CYP11B1 (0.57) | CYP3A4CYP11B1CYP11B2 | |
| SCHEMBL11603957 | 0.70 | TUBB4A (0.47) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL27456264 | 0.69 | TUBB4A (0.59) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL22474091 | 0.69 | CYP11B1 (0.64) | CYP3A4CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11059778-B2 | Cannabinoid receptor CB2 ligand 4-(aminomethyl)-N, N-dialkylanilines | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2021-07-13 | — | — | US | disclosed |
| US-20200270205-A1 | NOVEL CANNABINOID RECEPTOR CB2 LIGAND 4-(AMINOMETHYL)-N, N-DIALKYLANILINES | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2020-08-27 | — | — | US | disclosed |
| US-10696624-B2 | Cannabinoid receptor CB2 ligand 4-(aminomethyl)-N,N-dialkylanilines | University of Pittsburgh—of the Commonwealth System of Higher Education (US) | 2020-06-30 | — | — | US | disclosed |
| US-20180141902-A1 | NOVEL CANNABINOID RECEPTOR CB2 LIGAND 4-(AMINOMETHYL)-N,N-DIALKYLANILINES | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2018-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11059778-B2 | Cannabinoid receptor CB2 ligand 4-(aminomethyl)-N, N-dialkylanilines | CNR2, CNR1, GPR174 | TUBB4A 3593/4885TUBB 3578/4885TUBA3C 4127/4885 |
| US-20200270205-A1 | NOVEL CANNABINOID RECEPTOR CB2 LIGAND 4-(AMINOMETHYL)-N, N-DIALKYLANILINES | CNR2, CNR1, GPR174 | TUBB4A 3545/4885TUBB 3554/4885TUBA3C 4067/4885 |
| US-20180141902-A1 | NOVEL CANNABINOID RECEPTOR CB2 LIGAND 4-(AMINOMETHYL)-N,N-DIALKYLANILINES | CNR2, CNR1, GPR174 | TUBB4A 3559/4885TUBB 3594/4885TUBA3C 4225/4885 |
| US-10696624-B2 | Cannabinoid receptor CB2 ligand 4-(aminomethyl)-N,N-dialkylanilines | CNR2, CNR1, GPR174 | TUBB4A 3593/4885TUBB 3578/4885TUBA3C 4127/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.