Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | GPR183 | P32249 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23086975 | 1.00 | ALDH1A1 (0.50) | ALDH1A1FAAHCYP3A4CYP2D6MAPT | |
| SCHEMBL27990811 | 0.86 | HRH3 (0.52) | ALDH1A1FAAHMAPK1SIGMAR1LMNA | |
| SCHEMBL12545574 | 0.86 | ALDH1A1 (0.49) | ALDH1A1FAAHCYP3A4CYP2D6MAPT | |
| SCHEMBL4756430 | 0.84 | FAAH (0.52) | ALDH1A1FAAHGPR183LMNASMN1; SMN2 | |
| SCHEMBL8510915 | 0.81 | ITGB3 (0.56) | ALDH1A1CYP3A4CYP2D6MAPTMAPK1 | |
| SCHEMBL9610969 | 0.81 | ALDH1A1 (0.54) | ALDH1A1CYP3A4CYP2D6MAPTMAPK1 | |
| SCHEMBL7556163 | 0.81 | SIGMAR1 (0.65) | ALDH1A1FAAHSIGMAR1GPR183DRD4 | |
| SCHEMBL21044023 | 0.81 | ALDH1A1 (0.72) | ALDH1A1CYP3A4CYP2D6MAPTMAPK1 | |
| SCHEMBL16641754 | 0.81 | ALDH1A1 (0.72) | ALDH1A1CYP3A4CYP2D6MAPTMAPK1 | |
| SCHEMBL2717435 | 0.81 | ALDH1A1 (0.72) | ALDH1A1CYP3A4CYP2D6MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3541368-B1 | IMAGEABLE PARTICLES, METHODS OF MAKING AND METHODS OF USE THEREOF | US HEALTH (US) | 2023-07-12 | — | — | EP | disclosed |
| US-11382990-B2 | Imageable polymers, methods of making and methods of use thereof | THE USA, AS REPRESENTED BY THE SECRETARY, DHHS (US) | 2022-07-12 | — | — | US | disclosed |
| US-20200197540-A1 | Imageable Polymers, Methods of Making and Methods of Use Thereof | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES | 2020-06-25 | — | — | US | disclosed |
| WO-2018093566-A1 | IMAGEABLE PARTICLES, METHODS OF MAKING AND METHODS OF USE THEREOF | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2018-05-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11382990-B2 | Imageable polymers, methods of making and methods of use thereof | PUF60, PBRM1, PCBP1 | ALDH1A1 4268/4885FAAH 4063/4885CYP3A4 3651/4885 |
| US-20200197540-A1 | Imageable Polymers, Methods of Making and Methods of Use Thereof | PUF60, PBRM1, PCBP1 | ALDH1A1 4268/4885FAAH 4063/4885CYP3A4 3651/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.