SCHEMBL20180182

SCHEMBL20180182

CC1(C)OB(c2cccc(Nc3ccc4ccccc4c3C=N)c2)OC1(C)C

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EGFR P00533 3/20 0.40
LPL P06858 3/20 0.39
LIPG Q9Y5X9 3/20 0.39
FADS1 O60427 1/20 0.35
CDC25B P30305 2/20 0.34
ALDH1A1 P00352 1/20 0.34
TP53 P04637 1/20 0.34
CYP3A4 P08684 1/20 0.34
HPGD P15428 1/20 0.34
ALOX15 P16050 1/20 0.34
TSHR P16473 1/20 0.34
ATM Q13315 1/20 0.34
HSD17B10 Q99714 1/20 0.34
CA1 P00915 2/20 0.33
CA2 P00918 2/20 0.33
CA9 Q16790 2/20 0.33
IRAK4 Q9NWZ3 1/20 0.32
CA12 O43570 1/20 0.32
CA3 P07451 1/20 0.32
CA4 P22748 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20180154 0.85 LIPG (0.41) EGFRLPLLIPGCDC25BALDH1A1
SCHEMBL20180539 0.82 EGFR (0.42) EGFRLPLLIPGFADS1ALDH1A1
SCHEMBL20180141 0.82 LPL (0.37) EGFRLPLLIPGFADS1CDC25B
SCHEMBL20180164 0.81 LPL (0.41) EGFRLPLLIPGCA1CA2
SCHEMBL20180132 0.79 EGFR (0.42) EGFRLPLLIPGHPGDCA1
SCHEMBL20180275 0.77 EGFR (0.50) EGFRFADS1CDC25BALDH1A1TP53
SCHEMBL20180311 0.76 LIPG (0.47) EGFRLPLLIPGCA1CA2
SCHEMBL3758531 0.73 LIPG (0.50) EGFRLPLLIPGALDH1A1CYP3A4
SCHEMBL25491284 0.73 EGFR (0.42) EGFRLPLLIPGFADS1CA1
SCHEMBL20615284 0.72 ADRA2A (0.36) EGFRLPLLIPGCDC25BTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018093107-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING SAME 주식회사 두산 2018-05-24 WO disclosed