Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 6/20 | 0.40 |
| ▸ | PPARA | Q07869 | 4/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11130263 | 0.84 | ALDH1A1 (0.40) | ALDH1A1KMT2AMEN1L3MBTL1CYP3A4 | |
| SCHEMBL784043 | 0.82 | ELANE (0.41) | ALDH1A1KMT2AMEN1L3MBTL1CYP3A4 | |
| Methacrylic Acid SCHEMBL10770984 | 0.78 | ELANE (0.41) | ALDH1A1KMT2AMEN1L3MBTL1CYP3A4 | |
| SCHEMBL5850749 | 0.78 | THRB (0.46) | ALDH1A1KMT2AMEN1L3MBTL1CYP3A4 | |
| SCHEMBL1660600 | 0.78 | CA4 (0.48) | ALDH1A1KMT2AMEN1L3MBTL1CYP3A4 | |
| SCHEMBL7036896 | 0.77 | ALDH1A1 (0.40) | ALDH1A1L3MBTL1ELANEPPARGPPARA | |
| SCHEMBL7076942 | 0.77 | HIF1A (0.37) | ALDH1A1KMT2AMEN1L3MBTL1CYP3A4 | |
| SCHEMBL7538702 | 0.76 | PTGS2 (0.39) | ALDH1A1KMT2AMEN1L3MBTL1CYP3A4 | |
| SCHEMBL11513547 | 0.75 | L3MBTL1 (0.42) | ALDH1A1KMT2AMEN1L3MBTL1CYP3A4 | |
| SCHEMBL13072375 | 0.75 | PPARA (0.50) | ALDH1A1KMT2AMEN1L3MBTL1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018093924-A1 | CARBON MONOXIDE-RELEASING MOLECULES AND THERAPEUTIC APPLICATIONS THEREOF | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2018-05-24 | — | — | WO | disclosed |