Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP15 | Q460N3 | 1/20 | 0.49 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.49 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.49 |
| ▸ | PGR | P06401 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | IL18 | Q14116 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | MMP14 | P50281 | 1/20 | 0.40 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL335180 | 0.78 | — | — | |
| SCHEMBL7041250 | 0.78 | PARP15 (0.63) | PARP15PARP10PARP2PGRMAPT | |
| SCHEMBL8852392 | 0.78 | PARP15 (0.63) | PARP15PARP10PARP2PGRMAPT | |
| SCHEMBL3179628 | 0.76 | ALDH1A1 (0.56) | PARP10MAPTMEN1POLBMAPK1 | |
| SCHEMBL29582194 | 0.72 | PARP15 (0.57) | PARP15PARP10PARP2PGRMAPT | |
| SCHEMBL378478 | 0.70 | CYP19A1 (0.63) | PARP15PARP10PARP2PGRMAPT | |
| SCHEMBL4733455 | 0.69 | CYP19A1 (0.53) | PARP15PARP10PARP2PGRMAPT | |
| SCHEMBL7077780 | 0.69 | PARP15 (0.53) | PARP15PARP10PARP2PGRMAPT | |
| SCHEMBL921496 | 0.69 | MAOA (0.56) | PARP15PARP10PARP2MAPTCYP19A1 | |
| SCHEMBL4315032 | 0.69 | CA12 (0.73) | PARP15PARP10PARP2MAPTCYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10669237-B2 | 4-((6-bromopyridin-3-yl)oxy)benzonitrile and processes of preparation | DOW AGROSCIENCES LLC (US) | 2020-06-02 | — | — | US | disclosed |
| US-20190284139-A1 | 4-((6-BROMOPYRIDIN-3-YL)OXY)BENZONITRILE AND PROCESSES OF PREPARATION | CORTEVA AGRISCIENCE LLC | 2019-09-19 | — | — | US | disclosed |
| WO-2018094128-A1 | 4-((6-BROMOPYRIDIN-3-YL)OXY)BENZONITRILE AND PROCESSES OF PREPARATION | VPS-3, INC. (US) | 2018-05-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190284139-A1 | 4-((6-BROMOPYRIDIN-3-YL)OXY)BENZONITRILE AND PROCESSES OF PREPARATION | CYP3A4, BRD4, CYP4B1 | PARP15 1407/4885PARP10 1674/4885PARP2 585/4885 |
| US-10669237-B2 | 4-((6-bromopyridin-3-yl)oxy)benzonitrile and processes of preparation | CYP3A4, BRD4, CYP4B1 | PARP15 1407/4885PARP10 1674/4885PARP2 585/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.