Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.73 |
| ▸ | CA2 | P00918 | 1/20 | 0.73 |
| ▸ | CA3 | P07451 | 1/20 | 0.73 |
| ▸ | CA6 | P23280 | 1/20 | 0.73 |
| ▸ | CA9 | Q16790 | 1/20 | 0.73 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.73 |
| ▸ | MMP3 | P08254 | 1/20 | 0.64 |
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | ESR1 | P03372 | 1/20 | 0.64 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.64 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.58 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.58 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| P-Cresol SCHEMBL29176413 | 0.90 | ALDH1A1 (0.59) | CA12CA2CA3CA6CA9 | |
| Mequinol SCHEMBL6185858 | 0.90 | LTA4H (0.70) | CA12CA2CA3CA6CA9 | |
| SCHEMBL7041250 | 0.88 | PARP15 (0.63) | CA12CA2CA3CA6CA9 | |
| SCHEMBL8852392 | 0.88 | PARP15 (0.63) | CA12CA2CA3CA6CA9 | |
| SCHEMBL28781661 | 0.86 | PARP10 (0.63) | CA12CA2CA3CA6CA9 | |
| 4-Cyanophenol SCHEMBL50814 | 0.85 | — | — | |
| 4-Cyanophenol SCHEMBL27294505 | 0.85 | CA2 (1.00) | CA12CA2CA3CA6CA9 | |
| 4-Cyanophenol SCHEMBL28811803 | 0.85 | CA2 (1.00) | CA12CA2CA3CA6CA9 | |
| SCHEMBL1897244 | 0.85 | CA12 (0.52) | CA12CA2CA3CA6CA9 | |
| 4-Cyanophenol SCHEMBL7393582 | 0.83 | CA2 (0.94) | CA12CA2CA3CA6CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-59020292-A | — | — | None | — | — | JP | disclosed |
| CN-115536586-B | Pyrazole amide compound as well as preparation method and application thereof | 华东理工大学 | 2024-08-09 | — | — | CN | disclosed |
| CN-118290298-A | Benzoyl hydrazine compound and synthetic method and application thereof | 南京农业大学 | 2024-07-05 | — | — | CN | disclosed |
| CN-115536586-A | Pyrazole amide compounds and preparation method and application thereof | 华东理工大学 | 2022-12-30 | — | — | CN | disclosed |
| CN-101312948-B | Biaryl substituted heterocycle inhibitors of lTA4H for treating inflammation | DECODE GENETICS EHF | 2015-01-14 | — | — | CN | disclosed |
| EP-1926708-B1 | BIARYL SUBSTITUTED HETEROCYCLE INHIBITORS OF LTA4H FOR TREATING INFLAMMATION | DECODE GENETICS EHF (IS) | 2014-06-18 | — | — | EP | disclosed |
| US-8598359-B2 | Biaryl substituted heterocycle inhibitors of LTA4H for treating inflammation | DECODE GENETICS EHF (IS) | 2013-12-03 | — | — | US | disclosed |
| US-20090163462-A1 | BIARYL SUBSTITUTED HETEROCYCLE INHIBITORS OF LTA4H FOR TREATING INFLAMMATION | DECODE GENETICS, EHF (IS) | 2009-06-25 | — | — | US | disclosed |
| US-7402684-B2 | Biaryl substituted heterocycle inhibitors of LTA4H for treating inflammation | DECODE GENECTICS EHF. (IS) | 2008-07-22 | — | — | US | disclosed |
| EP-1926708-A1 | BIARYL SUBSTITUTED HETEROCYCLE INHIBITORS OF LTA4H FOR TREATING INFLAMMATION | Decode Chemistry, Inc. (US) | 2008-06-04 | — | — | EP | disclosed |
| US-20040006057-A1 | Triaryl-oxy-aryloxy-pyrimidine-2,4,6-trione metalloproteinase inhibitors | PFIZER PRODUCTS INC. | 2004-01-08 | — | — | US | disclosed |
| WO-2003090752-A1 | TRIARYL-OXY-ARYLOXY-PYRIMIDINE-2,4,6-TRIONE METALLOPROTEINASE INHIBITORS | PFIZER PRODUCTS INC. (US) | 2003-11-06 | — | — | WO | disclosed |
| US-6242654-B1 | REACTING A PHENOLATE COMPOUND WITH AN ORGANIC FLUORINATING AGENT TO PREPARE A FLUORINE SUBSTITUTED AROMATIC COMPOUND | MITSUI CHEMICALS, INC. (JP) | 2001-06-05 | — | — | US | disclosed |
| EP-1013629-A1 | Preparation process of fluorine subsituted aromatic compound | Mitsui Chemicals, Inc. (JP) | 2000-06-28 | — | — | EP | disclosed |
| EP-0303415-B1 | Herbicidally active phenoxy-alkanecarboxylic acid derivatives | SUNTORY LTD (JP) | 1994-11-30 | — | — | EP | disclosed |
| US-5205855-A | Postemergence, preemergence herbicides | SUNTORY LIMITED (JP) | 1993-04-27 | — | — | US | disclosed |
| US-4976773-A | SELECTIVITY BETWEEN MONOCOYLEDON PLANTS | SUNTORY LIMITED (JP) | 1990-12-11 | — | — | US | disclosed |
| EP-0303415-A2 | Herbicidally active phenoxy-alkanecarboxylic acid derivatives | SUNTORY LIMITED (JP) | 1989-02-15 | — | — | EP | disclosed |
| US-4608081-A | SELECTIVITY AGAINST GRASSES | KANESHO COMPANY LIMITED (JP) | 1986-08-26 | — | — | US | disclosed |
| JP-S5920292-A | ORGANIC PHOSPHORIC ESTER COMPOUND, ITS PREPARATION, INSECTICIDE AND ACARICIDE CONTAINING IT AS ACTIVE INGREDIENT | KANESHO KK | 1984-02-01 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040006057-A1 | Triaryl-oxy-aryloxy-pyrimidine-2,4,6-trione metalloproteinase inhibitors | MMP8, MMP9, MMP1 | CA12 3394/4885CA2 848/4885CA3 1719/4885 |
| US-20090163462-A1 | BIARYL SUBSTITUTED HETEROCYCLE INHIBITORS OF LTA4H FOR TREATING INFLAMMATION | LTA4H, LTB4R, LTC4S | CA12 4856/4885CA2 4722/4885CA3 4715/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.